Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16112201 | 0.78 | KDM4E (0.32) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL1260199 | 0.76 | — | — | |
| SCHEMBL28604731 | 0.71 | GABRR1 (0.37) | CYP2D6SMN1; SMN2 | |
| SCHEMBL15542332 | 0.70 | KDM4E (0.42) | NOS2KDM4EMAPTKMT2AATM | |
| SCHEMBL813890 | 0.70 | KDM4E (0.42) | NOS2KDM4EMAPTKMT2AATM | |
| SCHEMBL4286200 | 0.70 | — | — | |
| SCHEMBL2034681 | 0.69 | — | — | |
| SCHEMBL1982532 | 0.68 | — | — | |
| SCHEMBL31022855 | 0.68 | KDM4E (0.41) | NOS2KDM4EMAPTKMT2AATM | |
| SCHEMBL4730170 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1878725-B1 | Pyrimidine derivatives and their use as CB2 modulators | GLAXO GROUP LTD (GB) | 2010-11-24 | — | — | EP | disclosed |