SCHEMBL3382502

SCHEMBL3382502

CC12CC3CC(C1)C([SiH3])C(C)(C3)C2

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8947276 0.78 TSHR (0.33) TSHRLMNA
SCHEMBL2547155 0.78 TSHR (0.33) TSHRLMNA
SCHEMBL1930627 0.76 TSHR (0.32) TSHRLMNA
SCHEMBL6454576 0.76 TSHR (0.32) TSHRLMNA
SCHEMBL1697138 0.76 LMNA (0.33) TSHRLMNA
Hydrochloric Acid SCHEMBL3284553 0.74 LMNA (0.35) TSHRLMNA
SCHEMBL3382765 0.72 LMNA (0.36) TSHRLMNA
SCHEMBL28899300 0.71 SLC22A2 (0.31)
SCHEMBL733849 0.67 GRIN1 (0.48) TSHRLMNA
SCHEMBL3190483 0.67 GRIN1 (0.48) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1711550-B1 ADAMANTYL MONOMERS AND POLYMERS FOR LOW-K-DIELECTRIC APPLICATIONS SILECS OY (FI) 2010-12-01 EP claimed