Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 16/20 | 0.49 |
| ▸ | KDR | P35968 | 15/20 | 0.49 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385480 | 0.88 | KDR (0.48) | FGFR3KDRRETABL1KIT | |
| SCHEMBL3383795 | 0.87 | KDR (0.60) | FGFR3KDRRETABL1KIT | |
| SCHEMBL3384104 | 0.86 | FGFR3 (0.46) | FGFR3KDRRETABL1KIT | |
| SCHEMBL3383762 | 0.84 | KDR (0.45) | FGFR3KDRRETDDR1 | |
| SCHEMBL3383022 | 0.82 | FGFR3 (0.52) | FGFR3KDR | |
| SCHEMBL3184079 | 0.82 | FGFR3 (0.47) | FGFR3KDRRET | |
| SCHEMBL3197078 | 0.81 | FGFR3 (0.44) | FGFR3KDRRET | |
| SCHEMBL3385425 | 0.80 | KDR (0.44) | FGFR3KDR | |
| SCHEMBL3383240 | 0.79 | FGFR3 (0.49) | FGFR3KDR | |
| SCHEMBL3385522 | 0.78 | FGFR3 (0.61) | FGFR3KDRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |