Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 18/20 | 0.49 |
| ▸ | KDR | P35968 | 17/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383022 | 0.93 | FGFR3 (0.52) | FGFR3KDR | |
| SCHEMBL3382979 | 0.93 | FGFR3 (0.48) | FGFR3KDRWNT3A | |
| SCHEMBL3178478 | 0.90 | FGFR3 (0.52) | FGFR3KDR | |
| SCHEMBL3382504 | 0.88 | KDR (0.47) | FGFR3KDRWNT3A | |
| SCHEMBL3385467 | 0.88 | KDR (0.49) | FGFR3KDRWNT3A | |
| SCHEMBL3386163 | 0.88 | WNT3A (0.42) | FGFR3KDRWNT3A | |
| SCHEMBL3381090 | 0.87 | FGFR3 (0.49) | FGFR3KDRWNT3A | |
| SCHEMBL3189878 | 0.87 | KDR (0.49) | FGFR3KDR | |
| SCHEMBL3385477 | 0.87 | FGFR3 (0.41) | FGFR3KDR | |
| SCHEMBL3383517 | 0.86 | KDR (0.44) | FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |