Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | KDR | P35968 | 17/20 | 0.58 |
| ▸ | FGFR3 | P22607 | 15/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187469 | 0.90 | FGFR3 (0.59) | NPC1MAPTKDRFGFR3 | |
| SCHEMBL3186936 | 0.88 | FGFR3 (0.56) | KDRFGFR3 | |
| SCHEMBL3383649 | 0.86 | KDR (0.55) | KDRFGFR3 | |
| SCHEMBL3190830 | 0.85 | KDR (0.66) | KDRFGFR3 | |
| SCHEMBL3386132 | 0.84 | KDR (0.55) | MAPTKDRFGFR3 | |
| SCHEMBL3322217 | 0.83 | FGFR3 (0.82) | KDRFGFR3 | |
| SCHEMBL3386228 | 0.82 | KDR (0.55) | KDRFGFR3 | |
| SCHEMBL3189323 | 0.82 | KDR (0.59) | MAPTKDRFGFR3 | |
| SCHEMBL3198958 | 0.82 | KDR (0.70) | NPC1KDRFGFR3 | |
| SCHEMBL3417464 | 0.81 | FGFR3 (0.51) | KDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |