Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL4243136 | 1.00 | TSHR (0.71) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28509987 | 0.94 | TSHR (0.71) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL27832014 | 0.92 | TSHR (0.67) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL23071346 | 0.91 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28393368 | 0.91 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL23069370 | 0.91 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28906940 | 0.89 | TSHR (0.63) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL29117098 | 0.89 | TSHR (0.63) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Benzoic Acid SCHEMBL1913806 | 0.89 | TSHR (0.74) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL9017249 | 0.86 | TSHR (0.67) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220228315-A1 | METHOD FOR PRINTING ON NON-WOVEN TEXTILE SUBSTRATES USING RADIATION-CURING INKS | BASF COATINGS GMBH (DE) | 2022-07-21 | — | — | US | disclosed |
| EP-3959372-A1 | METHOD FOR PRINTING ON NON-WOVEN TEXTILE SUBSTRATES USING RADIATION-CURING INKS | BASF Coatings GmbH (DE) | 2022-03-02 | — | — | EP | disclosed |
| US-8097677-B2 | Mixtures containing thermoplastic polyurethane and acrylonitrile-styrene-acrylic ester copolymer (ASA) | BASF AKTIENGESELLSCHAFT (DE) | 2012-01-17 | — | — | US | disclosed |
| US-20060258805-A1 | Mixtures containing thermoplastic polyurethane and acrylonitrile-styrene-acrylic ester copolymer (asa) | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-16 | — | — | US | disclosed |
| US-6949285-B1 | comprises polyurethane elastomer with hard and soft segments and lithium borate | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-27 | — | — | US | disclosed |
| US-6559229-B1 | Blends of thermoplastic polyurethane having a Shore hardness of from 60 A to 50 D and ethylene-propylene (EPM) rubbers and/or modified ethylene- propylene (EPM) rubbers, ratios | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-06 | — | — | US | disclosed |
| US-6538075-B1 | Hardness, tensile and tear strength | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-25 | — | — | US | disclosed |
| US-6524712-B1 | Ratio of water vapor permeability level of a thermoplastic polyurethane to a styrene-based thermoplastic elastomer with alternating hard and soft segments is >/= 2 | WOLFF WALSRODE AG (DE) | 2003-02-25 | — | — | US | disclosed |
| US-6455618-B2 | FATTY ACID AMIDE ESTER WAX; NATURAL SILICA OR SYNTHETIC SILICA; OPTIONALLY MONTAN WAX | WOLFF WALSRODE AG (DE) | 2002-09-24 | — | — | US | disclosed |
| US-20020010240-A1 | Thermoplastic elastomer molding compositions with improved processability | EPUREX FILMS GMBH & CO. KG (DE) | 2002-01-24 | — | — | US | disclosed |
| US-6319985-B1 | ETHYLENE-PROPYLENE RUBBERS WHICH HAVE BEEN GRAFTED WITH ACRYLIC ACID, METHACRYLIC ACID, NON-AROMATIC DERIVATIVES OF ACRYLIC ACID OR METHACRYLIC ACID, MALEIC ANHYDRIDE, OR MALEIC ANHYDRIDE OR MIXTURES. | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-20 | — | — | US | disclosed |
| EP-1142044-A1 | MEMBRANE SUITABLE FOR ELECTROCHEMICAL CELLS | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-10 | — | — | EP | disclosed |
| US-6203915-B1 | Laminate | BASF COATINGS AG (DE) | 2001-03-20 | — | — | US | disclosed |
| WO-2000033406-A1 | MEMBRANE SUITABLE FOR ELECTROCHEMICAL CELLS | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-08 | — | — | WO | disclosed |
| US-5989715-A | Laminate | BASF COATINGS AG (DE) | 1999-11-23 | — | — | US | disclosed |