Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL338413 | 1.00 | TSHR (0.71) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28509987 | 0.94 | TSHR (0.71) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL27832014 | 0.92 | TSHR (0.67) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL23071346 | 0.91 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28393368 | 0.91 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL23069370 | 0.91 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28906940 | 0.89 | TSHR (0.63) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL29117098 | 0.89 | TSHR (0.63) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Benzoic Acid SCHEMBL1913806 | 0.89 | TSHR (0.74) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL9017249 | 0.86 | TSHR (0.67) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160193771-A1 | METHOD FOR PRODUCING SUPERFICIALLY CRYSTALLINE SPHERICAL GRANULES BY MEANS OF AIR-COOLED HOT DIE FACE PELLETIZING AND APPARATUS FOR CARRYING OUT THE METHOD | MAAG AUTOMATIK GMBH (DE) | 2016-07-07 | — | — | US | claimed |
| CN-107779989-B | Composite elastic fiber and preparation method thereof | 上海益弹新材料有限公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-106400168-A | Porous super-soft cotton-like polyester fiber, and preparation method thereof | 江苏恒力化纤股份有限公司 | 2017-02-15 | — | — | CN | disclosed |
| US-9512295-B2 | Polymer film, and phase difference film, polarizing plate and liquid crystal display device using the same | FUJIFILM CORPORATION (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20160193771-A1 | METHOD FOR PRODUCING SUPERFICIALLY CRYSTALLINE SPHERICAL GRANULES BY MEANS OF AIR-COOLED HOT DIE FACE PELLETIZING AND APPARATUS FOR CARRYING OUT THE METHOD | MAAG AUTOMATIK GMBH (DE) | 2016-07-07 | — | — | US | disclosed |
| CN-102717969-A | Packaging layer, method for manufacturing packaging pressure plate and packaging container produced therefrom | TETRA LAVAL HOLDINGS & FINANCE | 2012-10-10 | — | — | CN | disclosed |
| US-20090169775-A1 | POLYMER FILM, AND PHASE DIFFERENCE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | FUJIFILM CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |
| CN-1817417-A | Waste polyester gas purification | CHINA PETROCHEMICAL CORP (CN) | 2006-08-16 | — | — | CN | disclosed |
| CN-1556127-A | Dyeingable dalk coloured copolyester and its preparation method | 浙江恒逸集团有限公司 | 2004-12-22 | — | — | CN | disclosed |