Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 11/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381118 | 0.88 | NPC1 (0.54) | RAB9ANPC1FGFR3KDRFLT3 | |
| SCHEMBL3380805 | 0.88 | FLT3 (0.57) | RAB9ANPC1FGFR3KDRFLT3 | |
| SCHEMBL3189878 | 0.86 | KDR (0.49) | FGFR3KDRFLT3RET | |
| SCHEMBL3383229 | 0.86 | NPC1 (0.52) | RAB9ANPC1FLT3MAPK14MAPK13 | |
| SCHEMBL3198885 | 0.86 | NPC1 (0.53) | RAB9ANPC1FLT3MAPK14MAPK13 | |
| SCHEMBL3385839 | 0.85 | NPC1 (0.51) | RAB9ANPC1KDRFLT3MAPK14 | |
| SCHEMBL3381854 | 0.85 | NPC1 (0.49) | RAB9ANPC1FGFR3KDRFLT3 | |
| SCHEMBL3383068 | 0.85 | NPC1 (0.50) | RAB9ANPC1FGFR3KDRFLT3 | |
| SCHEMBL3383303 | 0.84 | NPC1 (0.52) | RAB9ANPC1KDRFLT3MAPK14 | |
| SCHEMBL3385155 | 0.84 | NPC1 (0.49) | RAB9ANPC1FLT3MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |