SCHEMBL338434

SCHEMBL338434

CCCCCCCCC(CC)Cc1[c]c2ccccc2cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
CSNK1E P49674 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CA2 P00918 1/20 0.33
CYP3A4 P08684 1/20 0.33
KDM4E B2RXH2 3/20 0.33
LMNA P02545 3/20 0.32
BDKRB2 P30411 1/20 0.31
HDAC3 O15379 2/20 0.31
HDAC1 Q13547 2/20 0.31
HDAC2 Q92769 2/20 0.31
HDAC8 Q9BY41 2/20 0.31
HDAC6 Q9UBN7 2/20 0.31
HDAC4 P56524 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3672634 0.94 PRSS1 (0.36) PRSS1PRSS2PRSS3CSNK1EALDH1A1
SCHEMBL3677149 0.94 PRSS1 (0.36) PRSS1PRSS2PRSS3CSNK1EALDH1A1
SCHEMBL3673724 0.94 PRSS1 (0.36) PRSS1PRSS2PRSS3CSNK1EALDH1A1
SCHEMBL3670260 0.94 PRSS1 (0.36) PRSS1PRSS2PRSS3CSNK1EALDH1A1
SCHEMBL3672762 0.94 PRSS1 (0.36) PRSS1PRSS2PRSS3CSNK1EALDH1A1
SCHEMBL3673169 0.94 PRSS1 (0.36) PRSS1PRSS2PRSS3CSNK1EALDH1A1
SCHEMBL3679150 0.94 PRSS1 (0.36) PRSS1PRSS2PRSS3CSNK1EALDH1A1
SCHEMBL2498870 0.94 ALDH1A1 (0.38) PRSS1PRSS2PRSS3ALDH1A1CA2
SCHEMBL3674992 0.94 PRSS1 (0.36) PRSS1PRSS2PRSS3CSNK1EALDH1A1
SCHEMBL3673683 0.93 PRSS1 (0.35) PRSS1PRSS2PRSS3CSNK1EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1809726-B1 USE OF 1,3-DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS LANXESS SOLUTIONS US INC (US) 2019-08-28 EP disclosed
EP-2207769-B1 ACRIDAN DERIVATIVES AS ANTIOXIDANTS CHEMTURA CORP (US) 2014-07-30 EP disclosed
EP-2209762-B1 DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS CHEMTURA CORP (US) 2013-11-20 EP disclosed
EP-1937767-B1 DIAROMATIC AMINES CHEMTURA CORP (US) 2013-05-22 EP disclosed
EP-1968955-B1 DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS CHEMTURA CORP (US) 2013-02-06 EP disclosed
EP-2497796-A2 Diaromatic Amines Chemtura Corporation (US) 2012-09-12 EP disclosed
EP-1833951-B1 DITHIOCARBAMYL ß-HYDROXY FATTY ACID ESTERS AS ADDITIVES FOR LUBRICANTS AND FUELS CHEMTURA CORP (US) 2012-08-22 EP disclosed
WO-2012011686-A3 CAMERA MODULE AND OPTICAL TOUCH SCREEN USING THE SAME LG INNOTEK CO., LTD. (KR) 2012-05-10 WO disclosed
US-8097731-B2 Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidalzoles with epoxides as lubricant additives CROMPTON CORPORATION (US) 2012-01-17 US disclosed
EP-1968985-B1 LUBRICATING OIL AND FUEL COMPOSITIONS CHEMTURA CORP (US) 2011-11-30 EP disclosed
EP-0391651-B1 Improved low ash lubricant composition for internal combustion engines EXXON CHEMICAL PATENTS INC (US) 1994-06-29 EP disclosed
US-5320765-A Low ash lubricant compositions for internal combustion engines EXXON CHEMICAL PATENTS INC. (US) 1994-06-14 US disclosed
US-5141657-A Mixture of dispersant, sulfurized alkylphenol and metal dihydrocarbyl dithiophosphate EXXON CHEMICAL PATENTS INC. (US) 1992-08-25 US disclosed
EP-0317354-B1 IMPROVED LUBRICANT COMPOSITIONS FOR ENHANCED FUEL ECONOMY EXXON CHEMICAL PATENTS INC. (US) 1992-07-08 EP disclosed
US-5102566-A Diesel fuel additive EXXON CHEMICAL PATENTS INC. (US) 1992-04-07 US disclosed
EP-0311319-B1 IMPROVED LUBRICANT COMPOSITIONS FOR INTERNAL COMBUSTION ENGINES EXXON CHEMICAL PATENTS INC. (US) 1991-08-21 EP disclosed
EP-0391651-A2 Improved low ash lubricant composition for internal combustion engines EXXON CHEMICAL PATENTS INC. (US) 1990-10-10 EP disclosed
EP-0317354-A1 Improved lubricant compositions for enhanced fuel economy EXXON CHEMICAL PATENTS INC. (US) 1989-05-24 EP disclosed
EP-0317348-A1 Improved lubricant compositions for low-temperature internal combustion engines EXXON CHEMICAL PATENTS INC. (US) 1989-05-24 EP disclosed
EP-0311319-A1 Improved lubricant compositions for internal combustion engines EXXON CHEMICAL PATENTS INC. (US) 1989-04-12 EP disclosed