Sebacic Acid

Sebacic Acid

SCHEMBL338445

CC(=O)C(C)=O.O=C(O)CCCCCCCCC(=O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.75
LMNA P02545 2/20 0.75
NFKB1 P19838 1/20 0.75
PMP22 Q01453 1/20 0.75
GPR84 Q9NQS5 8/20 0.65
PPARG P37231 7/20 0.65
PPARD Q03181 7/20 0.65
PPARA Q07869 7/20 0.65
HDAC11 Q96DB2 5/20 0.65
PTPN1 P18031 3/20 0.65
ALDH1A1 P00352 2/20 0.65
TLR2 O60603 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
FABP4 P15090 2/20 0.65
FFAR1 O14842 2/20 0.65
FFAR4 Q5NUL3 2/20 0.65
SLC22A6 Q4U2R8 2/20 0.65
SLC22A8 Q8TCC7 1/20 0.65
MEN1 O00255 1/20 0.65
ESR1 P03372 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL614869 0.97 LMNA (0.73) TSHRLMNANFKB1PMP22GPR84
Pimelic Acid SCHEMBL4948206 0.91 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
Pimelic Acid SCHEMBL28802731 0.90 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84
Octanedioate SCHEMBL1539264 0.90 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84
Acetone SCHEMBL28214433 0.90 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL15111284 0.90 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84
Azelaic Acid SCHEMBL1539243 0.90 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL3065275 0.90 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84
Acetic Acid SCHEMBL7845679 0.90 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84
Octanedioate SCHEMBL15111383 0.90 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2075013-B1 Patch package structure NITTO DENKO CORP (JP) 2016-03-16 EP disclosed
CN-101486400-B Patch package structure NITTO DENKO CORP 2012-10-10 CN disclosed
CN-101486401-B Patch package structure NITTO DENKO CORP 2012-06-20 CN disclosed
US-8096417-B2 Patch package structure NITTO DENKO CORPORATION (JP) 2012-01-17 US disclosed
US-8033395-B2 Patch package structure NITTO DENKO CORPORATION (JP) 2011-10-11 US disclosed
CN-101486400-A Patch package structure NITTO DENKO CORP (JP) 2009-07-22 CN disclosed
CN-101486401-A Patch package structure NITTO DENKO CORP (JP) 2009-07-22 CN disclosed
US-20090166229-A1 Patch package structure SASAKI CHEMICAL CO., LTD. (JP) 2009-07-02 US disclosed
US-20090166236-A1 Patch package structure NITTO DENKO CORPORATION (JP) 2009-07-02 US disclosed
EP-2075013-A2 Patch package structure Nitto Denko Corporation (JP) 2009-07-01 EP disclosed
EP-2070556-A2 Patch package structure Nitto Denko Corporation (JP) 2009-06-17 EP disclosed