⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4946257 | 0.71 | — | — | |
| SCHEMBL3383047 | 0.67 | THRB (0.53) | — | |
| SCHEMBL4780957 | 0.65 | — | — | |
| SCHEMBL6919 | 0.64 | — | — | |
| SCHEMBL4442942 | 0.64 | — | — | |
| SCHEMBL31243778 | 0.62 | — | — | |
| SCHEMBL29071846 | 0.60 | — | — | |
| SCHEMBL133547 | 0.60 | — | — | |
| SCHEMBL3384737 | 0.60 | — | — | |
| SCHEMBL31402248 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791851-B1 | PROCESS FOR PREPARATION OF ALKYL PHOSPHINATES | ASTRAZENECA AB (SE) | 2010-12-01 | — | — | EP | disclosed |
| US-20080319231-A1 | Process for the Preparation of Alkyl Phosphinates | ASTRAZENECA AB (SE) | 2008-12-25 | — | — | US | disclosed |
| EP-1791851-A1 | PROCESS FOR PREPARATION OF ALKYL PHOSPHINATES | AstraZeneca AB (SE) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006031180-A1 | PROCESS FOR PREPARATION OF ALKYL PHOSPHINATES | ASTRAZENECA AB (SE) | 2006-03-23 | — | — | WO | disclosed |