SCHEMBL3384844

SCHEMBL3384844

CC1NC(=O)NC1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6036786 1.00
SCHEMBL13233500 0.80 TSHR (0.38)
SCHEMBL11680526 0.78 TSHR (0.35)
SCHEMBL7611377 0.77
SCHEMBL19067687 0.76 TDP1 (0.33)
SCHEMBL36249 0.75 MAPT (0.39)
SCHEMBL36250 0.75 MAPT (0.39)
SCHEMBL10110596 0.74
SCHEMBL15999201 0.74 TDP1 (0.32)
SCHEMBL16234658 0.74 TDP1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025003925-A1 METHOD OF PREPARATION OF CHIMERIC HEMICUCURBIT[N]URILS, DERIVATIVES, AND USES THEREOF TALLINN UNIVERSITY OF TECHNOLOGY (EE) 2025-01-02 WO claimed
EP-4484422-A1 METHOD OF PREPARATION OF CHIMERIC HEMICUCURBIT[N]URILS, DERIVATIVES, AND USES THEREOF Tallinn University of Technology (EE) 2025-01-01 EP claimed
US-20030129191-A1 Pretargeting methods and compounds NEORX CORPORATION (US) 2003-07-10 US claimed
US-6416738-B1 ADMINISTERING TO A RECIPIENT A FIRST CONJUGATE COMPRISING A TARGETING MOIETY AND A MEMBER OF A LIGAND/ANTI-LIGAND BINDING PAIR, THEREAFTER ADMINISTERING TO THE RECIPIENT A CLEARING AGENT, ADMINISTERING SECOND CONJUGATE NEORX CORPORATION 2002-07-09 US claimed
US-6075010-A Small molecular weight ligand-hexose containing clearing agents NEORX CORPORATION (US) 2000-06-13 US claimed
EP-0743956-A4 PRETARGETING METHODS AND COMPOUNDS NEORX CORP (US) 1999-03-24 EP claimed
US-5624896-A Clearing agents useful in pretargeting methods NEORX CORPORATION (US) 1997-04-29 US claimed
EP-0743956-A1 PRETARGETING METHODS AND COMPOUNDS NeoRx (US) 1996-11-27 EP claimed
WO-1995015978-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO claimed
US-20260125394-A1 METHOD OF PREPARATION OF CHIMERIC HEMICUCURBIT[N]URILS, DERIVATIVES, AND USES THEREOF TALLINN UNIVERSITY OF TECHNOLOGY (EE) 2026-05-07 US disclosed
WO-2025003925-A1 METHOD OF PREPARATION OF CHIMERIC HEMICUCURBIT[N]URILS, DERIVATIVES, AND USES THEREOF TALLINN UNIVERSITY OF TECHNOLOGY (EE) 2025-01-02 WO disclosed
EP-4484422-A1 METHOD OF PREPARATION OF CHIMERIC HEMICUCURBIT[N]URILS, DERIVATIVES, AND USES THEREOF Tallinn University of Technology (EE) 2025-01-01 EP disclosed
EP-3283462-B1 FUSED-TRICYCLIC INHIBITORS OF KRAS AND METHODS OF USE THEREOF ARAXES PHARMA LLC (US) 2020-12-02 EP disclosed
EP-3733670-A1 TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF Mediconns (Shanghai) Biopharmaceutical Co., Ltd (CN) 2020-11-04 EP disclosed
EP-0794788-A1 HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF NEORX CORPORATION (US) 1997-09-17 EP disclosed
US-5624896-A Clearing agents useful in pretargeting methods NEORX CORPORATION (US) 1997-04-29 US disclosed
EP-0743956-A1 PRETARGETING METHODS AND COMPOUNDS NeoRx (US) 1996-11-27 EP disclosed
WO-1996017613-A1 HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF NEORX CORPORATION (US) 1996-06-13 WO disclosed
WO-1995015978-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO disclosed
EP-0132127-B1 CYCLIC UREA CONDENSATES, TEXTILE AND PAPER TREATING COMPOSITIONS AND NOVEL CYCLIC UREAS SEQUA CHEMICALS INC. (US) 1993-02-03 EP disclosed