⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497854 | 1.00 | — | — | |
| SCHEMBL6269532 | 0.84 | TDP1 (0.36) | — | |
| SCHEMBL14026498 | 0.78 | — | — | |
| SCHEMBL12663905 | 0.78 | — | — | |
| SCHEMBL13448397 | 0.75 | TDP1 (0.44) | — | |
| SCHEMBL20123222 | 0.75 | TDP1 (0.44) | — | |
| SCHEMBL13448308 | 0.75 | TDP1 (0.44) | — | |
| SCHEMBL6561453 | 0.74 | ABL1 (0.65) | — | |
| SCHEMBL3384844 | 0.74 | — | — | |
| SCHEMBL6036786 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190330693-A1 | SINGLE FLUORESCENT DYE-BASED SEQUENCING METHOD | Qingdao MGI Tech Co., Ltd. (CN) | 2019-10-31 | — | — | US | disclosed |
| US-20180127822-A1 | MODIFIED NUCLEOTIDES METHODS AND KITS | PIERCE BIOTECHNOLOGY, INC. (US) | 2018-05-10 | — | — | US | disclosed |
| EP-2203161-B1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | UNIV INDIANA RES & TECH CORP (US) | 2018-05-09 | — | — | EP | disclosed |
| US-9828633-B1 | Modified nucleotides methods and kits | PIERCE BIOTECHNOLOGY, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| US-20120157403-A1 | BICYCLIC AND TRICYCLIC DERIVATIVES AS THROMBIN RECEPTOR ANTAGONISTS | CHACKALAMANNIL SAMUEL (US) | 2012-06-21 | — | — | US | disclosed |
| US-20080090830-A1 | Bicyclic And Tricyclic Derivatives As Thrombin Receptor Antagonists | SCHERING CORPORATION | 2008-04-17 | — | — | US | disclosed |