SCHEMBL3384953

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2369089	0.92	KCNH2 (0.67)	KCNH2TNFNOD1MAPK1KCNA5
	SCHEMBL3386430	0.88	TNF (0.53)	KCNH2TNFNOD1MAPK1KCNA5
	SCHEMBL3386735	0.87	TNF (0.59)	KCNH2TNFNOD1MAPK1KCNA5
	SCHEMBL2368786	0.85	TNF (0.57)	KCNH2TNFNOD1MAPK1KCNA5
	SCHEMBL3385334	0.85	ESR1 (0.61)	KCNH2TNFNOD1MAPK1KCNA5
	SCHEMBL2368795	0.85	TNF (0.59)	KCNH2TNFNOD1MAPK1KCNA5
	SCHEMBL2368683	0.82	TNF (0.56)	KCNH2TNFNOD1MAPK1KCNA5
	SCHEMBL2368804	0.82	TNF (0.55)	KCNH2TNFNOD1MAPK1KCNA5
	SCHEMBL2369260	0.82	TNF (0.55)	KCNH2TNFNOD1MAPK1KCNA5
	SCHEMBL3387956	0.81	TNF (0.83)	TNFNOD1MAPK1KCNA5PIP4K2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.