SCHEMBL3385243

SCHEMBL3385243

Cl[Hf](Cl)(Cl)C1C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
HTR6 P50406 1/20 0.37
SIGMAR1 Q99720 2/20 0.31
CYP2D6 P10635 2/20 0.31
KDM4E B2RXH2 2/20 0.31
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819247 0.87 HTR6 (0.41) HTR2AHTR6SIGMAR1CYP2D6KDM4E
Ethylene SCHEMBL9289285 0.83 HTR6 (0.39) HTR2AHTR6
SCHEMBL8584151 0.79 HTR6 (0.36) HTR2AHTR6SIGMAR1CYP2D6KDM4E
SCHEMBL9075828 0.79 HTR6 (0.33) HTR2AHTR6SIGMAR1CYP2D6KDM4E
SCHEMBL3382688 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1CYP2D6KDM4E
SCHEMBL3382000 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1CYP2D6KDM4E
SCHEMBL3382947 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1CYP2D6KDM4E
SCHEMBL8380950 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1CYP2D6KDM4E
SCHEMBL28290857 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1CYP2D6KDM4E
SCHEMBL7641586 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1CYP2D6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709586-B2 Olefin polymerization catalyst and olefin polymerization process using the same DAELIM INDUSTRIAL CO., LTD. (KR) 2010-05-04 US disclosed
US-20070142221-A1 Olefin polymerization catalyst and olefin polymerization process using the same DAELIM INDUSTRIAL CO., LTD. 2007-06-21 US disclosed
EP-0716092-B1 Organic transition metal compound and process for the preparation of polyolefin using same TOSOH CORP (JP) 2000-10-25 EP disclosed
US-5916982-A Process for the production of polyolefins NIPPON OIL CO., LTD. (JP) 1999-06-29 US disclosed
US-5770666-A METALLOCENE TOSOH CORPORATION (JP) 1998-06-23 US disclosed
US-5744666-A Process for preparing an alkynyl fulvene group containing compound and said compound PHILLIPS PETROLEUM COMPANY (US) 1998-04-28 US disclosed
US-5728908-A Process for preparing a bridged ligand and said bridged ligand PHILLIPS PETROLEUM COMPANY (US) 1998-03-17 US disclosed
US-5631203-A Metallocene compounds and preparation thereof containing terminal alkynes PHILLIPS PETROLEUM COMPANY (US) 1997-05-20 US disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0768319-A1 Process for the production of polyolefins NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0716092-A1 Organic transition metal compound and process for the preparation of polyolefin using same TOSOH CORPORATION (JP) 1996-06-12 EP disclosed