Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL3384054 | 0.96 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL3384912 | 0.96 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL30811904 | 0.96 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Bromide SCHEMBL3385664 | 0.96 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL524602 | 0.82 | PNMT (0.63) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL30103334 | 0.82 | PNMT (0.63) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL2877998 | 0.80 | PNMT (0.61) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL22263591 | 0.77 | PNMT (0.57) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL27885618 | 0.76 | PNMT (0.57) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL9055014 | 0.75 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709586-B2 | Olefin polymerization catalyst and olefin polymerization process using the same | DAELIM INDUSTRIAL CO., LTD. (KR) | 2010-05-04 | — | — | US | disclosed |
| US-20070142221-A1 | Olefin polymerization catalyst and olefin polymerization process using the same | DAELIM INDUSTRIAL CO., LTD. | 2007-06-21 | — | — | US | disclosed |