SCHEMBL338568

SCHEMBL338568

NC(=O)c1cc(=O)cc[nH]1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCNC P24863 6/20 0.43
▸ CDK8 P49336 6/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ HTT P42858 2/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ ALOX15 P16050 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ BLM P54132 1/20 0.38
▸ ALDH1A1 P00352 3/20 0.38
▸ MAP2K1 Q02750 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ MTNR1A P48039 1/20 0.38
▸ MTNR1B P49286 1/20 0.38
▸ PDPK1 O15530 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ CTSA P10619 1/20 0.36
▸ PKM P14618 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ IKBKB O14920 1/20 0.35
▸ CHUK O15111 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18473861 0.79 SMN1; SMN2 (0.56) SMN1; SMN2KMT2AALOX15NFKB1BLM
Hydrochloric Acid SCHEMBL30564912 0.77 SMN1; SMN2 (0.54) SMN1; SMN2KMT2AALOX15NFKB1BLM
Hydrochloric Acid SCHEMBL10721520 0.76 CTSA (0.38) SMN1; SMN2KMT2AALOX15NFKB1BLM
SCHEMBL29044976 0.74 CTSA (0.43) SMN1; SMN2ALOX15NFKB1BLMCTSA
SCHEMBL6782595 0.71 TSHR (0.50) SMN1; SMN2KMT2ARAB9A
SCHEMBL30350 0.71 — —
SCHEMBL6163681 0.71 MEN1 (0.44) CCNCCDK8SMN1; SMN2KMT2ABLM
Hydrochloric Acid SCHEMBL6052939 0.70 — —
Bromide SCHEMBL3617299 0.70 — —
Fluoride SCHEMBL28479463 0.70 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112064023-A High-wear-resistance plating chromium process and ABS/PC material for mobile phone frame 深圳市生利科技有限公司 2020-12-11 — — CN claimed
CN-112064020-A Aluminum plating process with good coating permeability prevention and mobile phone frame ABS/PC material 深圳市生利科技有限公司 2020-12-11 — — CN claimed
CN-112030149-A Chromium plating process for ABS/PC plastic 深圳市生利科技有限公司 2020-12-04 — — CN claimed
CN-113286793-B Inhibitors of influenza virus replication of pyrrolopyrazines and pyridotriazines 共结晶制药公司 2024-04-05 — — CN disclosed
CN-115896884-A Chromium plating process for ABS-based plastic alloy surface and product 深圳市生利科技有限公司 2023-04-04 — — CN disclosed
CN-112064023-A High-wear-resistance plating chromium process and ABS/PC material for mobile phone frame 深圳市生利科技有限公司 2020-12-11 — — CN disclosed
CN-112064020-A Aluminum plating process with good coating permeability prevention and mobile phone frame ABS/PC material 深圳市生利科技有限公司 2020-12-11 — — CN disclosed
CN-112030149-A Chromium plating process for ABS/PC plastic 深圳市生利科技有限公司 2020-12-04 — — CN disclosed
EP-1687298-B1 CYCLOALKYL DERIVATIVES OF 3-HYDROXY-4-PYRIDINONES APOTEX INC (CA) 2012-12-26 — — EP disclosed
EP-1824823-B1 PROCESS FOR THE MANUFACTURE OF 3-HYDROXY-N-ALKYL-1-CYCLOALKYL-6-ALKYL-4-OXO-1,4-DIHYDROPYRIDINE-2-CARBOXAMIDE AND ITS RELATED ANALOGUES APOTEX INC (CA) 2012-04-25 — — EP disclosed
US-8097624-B2 Cycloalkyl derivatives of 3-hydroxy-4-pyridinones APOTEX INC. (CA) 2012-01-17 — — US disclosed
EP-1440061-B1 PROCESSES FOR THE MANUFACTURING OF 3-HYDROXY-N,1,6-TRIALKYL-4-OXO-1,4-DIHYDROPYRIDINE-2-CARBOXAMIDE APOTEX INC (CA) 2007-04-11 — — EP disclosed
EP-1687298-A1 CYCLOALKYL DERIVATIVES OF 3-HYDROXY-4-PYRIDINONES Apotex Inc. (CA) 2006-08-09 — — EP disclosed
WO-2006053429-A1 PROCESS FOR THE MANUFACTURE OF 3-HYDROXY-N-ALKYL-1-CYCLOALKYL-6-ALKYL-4-OXO-1,4-DIHYDROPYRIDINE-2-CARBOXAMIDE AND ITS RELATED ANALOGUES APOTEX INC. (CA) 2006-05-26 — — WO disclosed
WO-2005049609-A1 CYCLOALKYL DERIVATIVES OF 3-HYDROXY-4-PYRIDINONES APOTEX INC. (CA) 2005-06-02 — — WO disclosed
EP-1440061-A1 PROCESSES FOR THE MANUFACTURING OF 3-HYDROXY-N,1,6-TRIALKYL-4-OXO-1,4-DIHYDROPYRIDINE-2-CARBOXAMIDE APOTEX INC. (CA) 2004-07-28 — — EP disclosed
WO-2003037867-A1 PROCESSES FOR THE MANUFACTURING OF 3-HYDROXY-N,1,6-TRIALKYL-4-OXO-1,4-DIHYDROPYRIDINE-2-CARBOXAMIDE APOTEX INC. (CA) 2003-05-08 — — WO disclosed
US-6476229-B1 Processes for the manufacturing of 3-hydroxy-N,1,6-trialkyl-4-oxo-1,4-dihydropyridine-2-carboxamide APOTEX, INC. (CA) 2002-11-05 — — US disclosed
US-6472532-B1 INEXPENSIVE METHOD USING KOJIC ACID AS SAFE STARTING MATERIAL FOR SYNTHESIS OF ORALLY ACTIVE IRON CHELATORS APOTEX, INC. (CA) 2002-10-29 — — US disclosed
US-6426418-B1 REACTING A 3-OXY-2-HYDROXYALKYL-4H-PYRAN-4-ONE DERIVATIVE WITH SODIUM HYPOCHLORITE SOLUTION, POTASSIUM BROMIDE, TEMPO, AND A PHASE TRANSFER CATALYST TO PRODUCE A 3-OXY-2-CARBOXY-4H-PYRAN-4-ONE DERIVATIVE APOTEX, INC. (CA) 2002-07-30 — — US disclosed
Send feedback