SCHEMBL3385698

SCHEMBL3385698

CC(C)(C)OC(=O)O[C@H]1CCC(=O)N1OC(=O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15520352 0.79 CHRM2 (0.40) CHRM2CHRM1CHRM3DDB1CRBN
SCHEMBL372025 0.70 ELANE (0.34) CHRM2CHRM1CHRM3ALDH1A1KMT2A
SCHEMBL3382234 0.69 CHRM2 (0.35) CHRM2CHRM1CHRM3
SCHEMBL15519566 0.68 GLA (0.37) CHRM2CHRM1CHRM3DDB1CRBN
SCHEMBL3383542 0.68 DDB1 (0.33) DDB1CRBN
SCHEMBL18946973 0.67 CHRM2 (0.32) CHRM2CHRM1CHRM3
SCHEMBL30360895 0.67 CHRM2 (0.40) CHRM2CHRM1CHRM3DDB1CRBN
SCHEMBL22795837 0.66 KDM4E (0.34) DDB1CRBN
SCHEMBL5678652 0.65 CHRM2 (0.39) CHRM2CHRM1CHRM3ELANE
SCHEMBL31125471 0.65 ATM (0.35) CHRM2CHRM1CHRM3DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651649-B1 NOVEL CYANOPYRROLIDIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICATION SANOFI AVENTIS DEUTSCHLAND (DE) 2010-12-01 EP disclosed
EP-1651649-A1 NOVEL CYANOPYRROLIDIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS Sanofi-Aventis Deutschland GmbH (DE) 2006-05-03 EP disclosed
WO-2005012308-A1 NOVEL CYANOPYRROLIDIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2005-02-10 WO disclosed