Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15752214 | 0.71 | LMNA (0.32) | MAPT | |
| SCHEMBL5742787 | 0.71 | PREP (0.32) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL3706193 | 0.70 | — | — | |
| SCHEMBL6210049 | 0.70 | ELANE (0.37) | — | |
| SCHEMBL4962721 | 0.69 | — | — | |
| SCHEMBL2564447 | 0.68 | USP2 (0.33) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL3385698 | 0.68 | CHRM2 (0.33) | DDB1CRBN | |
| SCHEMBL372025 | 0.67 | ELANE (0.34) | — | |
| SCHEMBL5036518 | 0.66 | ESR2 (0.33) | — | |
| SCHEMBL8455130 | 0.66 | HPGD (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651649-B1 | NOVEL CYANOPYRROLIDIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICATION | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-12-01 | — | — | EP | disclosed |