Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.62 |
| ▸ | METAP2 | P50579 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | COMT | P21964 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | METAP1 | P53582 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Jineol SCHEMBL4213727 | 0.80 | KDM4E (0.67) | KDM4EMETAP2MMP2CHRM1TSHR | |
| Jineol SCHEMBL29696064 | 0.80 | KDM4E (0.67) | KDM4EMETAP2MMP2CHRM1TSHR | |
| Jineol SCHEMBL28133873 | 0.78 | KDM4E (0.65) | KDM4EMETAP2MMP2CHRM1TSHR | |
| SCHEMBL2197162 | 0.77 | KMT2A (0.41) | KDM4ETSHRMEN1KMT2AMAPT | |
| SCHEMBL14923574 | 0.77 | KDM4E (0.38) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5558125 | 0.77 | NR4A2 (0.38) | KDM4EPLAUMAPTALDH1A1LMNA | |
| SCHEMBL14661368 | 0.77 | KDM4E (0.44) | KDM4EMAPTALDH1A1 | |
| SCHEMBL3704824 | 0.77 | KDM4E (0.62) | KDM4EMETAP2MMP2CHRM1TSHR | |
| SCHEMBL18229801 | 0.77 | KDM4E (0.62) | KDM4EMETAP2MMP2CHRM1TSHR | |
| SCHEMBL14046290 | 0.77 | KDM4E (0.62) | KDM4EMETAP2MMP2CHRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4623914-A1 | USE OF 8-HYDROXYQUINOLINE DERIVATIVE | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2025-10-01 | — | — | EP | disclosed |
| CN-120035438-A | Use of 8-hydroxyquinoline derivatives | 江苏亚虹医药科技股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-119307988-A | Antioxidant for methylsulfonic acid tinning and preparation method thereof | 宝山钢铁股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| US-20240246916-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF | JIANGSU YAHONG MEDITECH CO., LTD. (CN) | 2024-07-25 | — | — | US | disclosed |
| WO-2024109684-A1 | USE OF 8-HYDROXYQUINOLINE DERIVATIVE | 江苏亚虹医药科技股份有限公司 | 2024-05-30 | — | — | WO | disclosed |
| CN-118059101-A | Use of 8-hydroxyquinoline derivatives | 江苏亚虹医药科技股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-4349815-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2024-04-10 | — | — | EP | disclosed |
| CN-117043141-A | 7-nitro-8-hydroxyquinoline derivative, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-117015845-A | Composition for cleaning semiconductor substrate and cleaning method | 三菱瓦斯化学株式会社 | 2023-11-07 | — | — | CN | disclosed |
| WO-2022253152-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |
| WO-2012002577-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | 富士フイルム株式会社 (JP) | 2012-01-05 | — | — | WO | disclosed |
| US-7759372-B2 | Nitrogen-containing heteroaryl compounds having inhibitory activity against HIV integrase | SHIONOGI & CO., LTD. (JP) | 2010-07-20 | — | — | US | disclosed |
| US-7759372-B2 | Nitrogen-containing heteroaryl compounds having inhibitory activity against HIV integrase | SHIONOGI & CO., LTD. (JP) | 2010-07-20 | — | — | US | disclosed |
| US-7504046-B2 | Polymer grafted alkaline earth aluminate phosphor through coordination bond | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2009-03-17 | — | — | US | disclosed |
| US-7504046-B2 | Polymer grafted alkaline earth aluminate phosphor through coordination bond | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2009-03-17 | — | — | US | disclosed |
| EP-2033952-A1 | Nitrogen-containing Heteroaryl compounds having HIV Integrase Inhibitory Activity | Shionogi&Co., Ltd. (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7332232-B2 | OLEDs utilizing multidentate ligand systems | UNIVERSAL DISPLAY CORPORATION (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332232-B2 | OLEDs utilizing multidentate ligand systems | UNIVERSAL DISPLAY CORPORATION (US) | 2008-02-19 | — | — | US | disclosed |
| US-20070221886-A1 | Polymer grafted alkali earth aluminate phosphor through coordination bond | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2007-09-27 | — | — | US | disclosed |
| US-20070221886-A1 | Polymer grafted alkali earth aluminate phosphor through coordination bond | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246916-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF | CYP3A7, UGT1A7, UGT2B7 | KDM4E 2921/4885METAP2 3111/4885MMP2 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.