Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propanol SCHEMBL5398171 | 0.87 | — | — | |
| Ethylene Glycol SCHEMBL9004896 | 0.87 | — | — | |
| Methyl Alcohol SCHEMBL28240487 | 0.86 | — | — | |
| Acetone SCHEMBL20239121 | 0.86 | ALDH1A1 (0.40) | — | |
| SCHEMBL221 | 0.85 | — | — | |
| SCHEMBL958930 | 0.85 | TSHR (0.36) | — | |
| SCHEMBL453616 | 0.85 | — | — | |
| SCHEMBL8087800 | 0.80 | — | — | |
| SCHEMBL3181069 | 0.80 | — | — | |
| SCHEMBL11660320 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061966-B | Bicyclic heterocycle derivatives as bromodomain inhibitor | 奥赖恩公司 | 2018-12-07 | — | — | CN | disclosed |
| US-20100113550-A1 | New Crystal Forms | BIAL - PORTELA AND CA, S.A. (PT) | 2010-05-06 | — | — | US | disclosed |