Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.75 |
| ▸ | LMNA | P02545 | 9/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 6/20 | 0.66 |
| ▸ | TSHR | P16473 | 6/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.66 |
| ▸ | SNCA | P37840 | 4/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.66 |
| ▸ | PGR | P06401 | 4/20 | 0.66 |
| ▸ | AR | P10275 | 4/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.66 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.66 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.66 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15307732 | 1.00 | SHBG (0.75) | SHBGLMNACYP3A4HSD17B10SERPINA6 | |
| SCHEMBL10080165 | 0.87 | CYP3A4 (0.64) | SHBGLMNACYP3A4HSD17B10SERPINA6 | |
| SCHEMBL1899372 | 0.86 | SHBG (1.00) | SHBGLMNACYP3A4HSD17B10SERPINA6 | |
| SCHEMBL4102864 | 0.86 | SHBG (1.00) | SHBGLMNACYP3A4HSD17B10SERPINA6 | |
| SCHEMBL4102861 | 0.86 | SHBG (1.00) | SHBGLMNACYP3A4HSD17B10SERPINA6 | |
| SCHEMBL13752654 | 0.86 | SHBG (1.00) | SHBGLMNACYP3A4HSD17B10SERPINA6 | |
| SCHEMBL1899376 | 0.86 | SHBG (1.00) | SHBGLMNACYP3A4HSD17B10SERPINA6 | |
| SCHEMBL1900826 | 0.86 | SHBG (1.00) | SHBGLMNACYP3A4HSD17B10SERPINA6 | |
| SCHEMBL4895186 | 0.85 | SHBG (0.77) | SHBGLMNACYP3A4HSD17B10SERPINA6 | |
| SCHEMBL18799945 | 0.85 | SHBG (0.77) | SHBGLMNACYP3A4HSD17B10SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019114-B1 | Process for the preparation of Drospirenone | NEWCHEM S P A (IT) | 2010-12-15 | — | — | EP | disclosed |
| EP-2019114-A1 | Process for the preparation of Drospirenone | Newchem S.p.A. (IT) | 2009-01-28 | — | — | EP | disclosed |