SCHEMBL3387487

SCHEMBL3387487

CSc1ccc2ccccc2c1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP1A2 P05177 4/20 0.46
AKR1C3 P42330 3/20 0.46
AKR1C2 P52895 3/20 0.46
EPHX1 P07099 1/20 0.46
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
ALOX12 P18054 1/20 0.42
UGT2B7 P16662 1/20 0.41
ANPEP P15144 1/20 0.41
NOX1 Q9Y5S8 1/20 0.41
HAO1 Q9UJM8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11909803 1.00 CYP2A6 (0.50) CYP2A6TDP1CYP1A2AKR1C3AKR1C2
SCHEMBL29507310 1.00 CYP2A6 (0.50) CYP2A6TDP1CYP1A2AKR1C3AKR1C2
SCHEMBL26224853 0.92 ALDH1A1 (0.46) CYP2A6TDP1CYP1A2AKR1C3AKR1C2
SCHEMBL29740644 0.89 AKR1C3 (0.52) CYP2A6TDP1CYP1A2AKR1C3AKR1C2
SCHEMBL8637909 0.89 AKR1C3 (0.52) CYP2A6TDP1CYP1A2AKR1C3AKR1C2
Phosphonic Acid SCHEMBL7761460 0.87 AKR1C3 (0.46) CYP2A6TDP1CYP1A2AKR1C3AKR1C2
SCHEMBL29740639 0.86 AKR1C3 (0.45) CYP2A6TDP1CYP1A2AKR1C3AKR1C2
SCHEMBL21551821 0.86 AKR1C3 (0.45) CYP2A6TDP1CYP1A2AKR1C3AKR1C2
SCHEMBL21898203 0.84 ESR1 (0.55) CYP2A6TDP1CYP1A2ALDH1A1CA1
SCHEMBL29180421 0.83 AKR1C3 (0.48) CYP2A6TDP1CYP1A2AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486662-A Method for synthesizing sulfoxide compound by heterogeneous catalysis 成都理工大学 2024-02-02 CN claimed
CN-116459830-A Preparation method of fluorine/carbon co-doped titanium dioxide noble metal cluster photocatalyst material 长沙尚洁环保科技有限公司 2023-07-21 CN claimed
CN-115305243-B Baeyer-Villiger monooxygenase mutant and application thereof 江南大学 2023-06-02 CN claimed
CN-115044566-B Cyclohexanone monooxygenase mutant and application thereof 江南大学 2023-05-02 CN claimed
CN-115305243-A Baeyer-Villiger monooxygenase mutant and application thereof 江南大学 2022-11-08 CN claimed
CN-115044566-A Cyclohexanone monooxygenase mutant and application thereof 江南大学 2022-09-13 CN claimed
CN-114591290-A Preparation method of substituted benzo [ B ] naphthalene benzene [2, 3-D ] thiophene derivative and derivative 陕西维世诺新材料有限公司 2022-06-07 CN claimed
CN-108727902-A Inorganic nano material prints ink and preparation method thereof TCL集团股份有限公司 2018-11-02 CN claimed
EP-2057148-B1 AMIDINE DERIVATIVES OF 2-HETEROARYL-QUINAZOLINES AND QUINOLINES; POTENT ANALGESICS AND ANTI-INFLAMMATORY AGENTS ROTTAPHARM SPA (IT) 2009-12-30 EP claimed
US-20080118969-A1 BIS-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE LLC (US) 2008-05-22 US claimed
US-5753660-A Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors G. D. SEARLE & CO. (US) 1998-05-19 US claimed
US-5705500-A HIV TREATMENT G.D. SEARLE & CO. (US) 1998-01-06 US claimed
EP-0813519-A1 SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1997-12-29 EP claimed
EP-0813543-A1 BIS-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1997-12-29 EP claimed
WO-1997018205-A1 SUBSTITUTED SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1997-05-22 WO claimed
US-5618804-A TREATING INFLAMMATION, RHEUMATISM, BONE METABOLIC DISEASES; INHIBIT INTERLEUKIN PRODUCTION, ACTIVE OXYGEN PRODUCTION, BONE RESORPTION TORAY INDUSTRIES, INC. (JP) 1997-04-08 US claimed
WO-1996028464-A1 BIS-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-09-19 WO claimed
WO-1996028418-A1 SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-09-19 WO claimed
WO-1996028463-A1 AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-09-19 WO claimed
EP-0192492-B1 PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-01-02 EP claimed