⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17963697 | 0.76 | — | — | |
| SCHEMBL1042894 | 0.74 | — | — | |
| SCHEMBL27905686 | 0.73 | — | — | |
| SCHEMBL2294954 | 0.71 | — | — | |
| SCHEMBL27833343 | 0.69 | — | — | |
| SCHEMBL27905787 | 0.69 | — | — | |
| SCHEMBL1515279 | 0.69 | — | — | |
| SCHEMBL1116189 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL10181570 | 0.69 | — | — | |
| SCHEMBL11756972 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015792-A1 | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | MSD K.K. (JP) | 2007-01-18 | — | — | US | claimed |
| CN-101223158-B | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | BANYU PHARMA CO LTD | 2013-01-09 | — | — | CN | disclosed |
| EP-1914232-B1 | N-DIHYDROXYALKYL-SUBSTITUTED 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2010-12-15 | — | — | EP | disclosed |
| CN-101223158-A | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | BANYU PHARMA CO LTD (JP) | 2008-07-16 | — | — | CN | disclosed |
| US-20080103178-A1 | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | MSD K.K. (JP) | 2008-05-01 | — | — | US | disclosed |
| EP-1914232-A1 | N-DIHYDROXYALKYL-SUBSTITUTED 2-OXOIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-7300947-B2 | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-20070015792-A1 | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | MSD K.K. (JP) | 2007-01-18 | — | — | US | disclosed |
| EP-0938478-A1 | QUATERNARY NITROGEN HETEROCYCLES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998022444-A1 | QUATERNARY NITROGEN HETEROCYCLES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1998-05-28 | — | — | WO | disclosed |