SCHEMBL338756

SCHEMBL338756

N[C@H](O)CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL447923 1.00
SCHEMBL27918470 1.00
Hydrochloric Acid SCHEMBL27348202 0.97
Benzene SCHEMBL28834032 0.94 SLC22A6 (0.50)
SCHEMBL288510 0.76 SLC22A6 (0.50)
SCHEMBL93579 0.76
SCHEMBL2491274 0.76 SLC22A6 (0.50)
SCHEMBL23225427 0.75
SCHEMBL4797239 0.75
SCHEMBL29305546 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018567-A1 METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES BECTON DICKINSON CO (US) 2024-01-18 US disclosed
US-11572579-B2 Kits for the detection of beta-lactamases BECTON, DICKINSON AND COMPANY (US) 2023-02-07 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20210155969-A1 METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES BECTON DICKINSON CO (US) 2021-05-27 US disclosed
US-10704079-B2 Methods for the detection of beta-lactamases in a sample BECTON, DICKINSON AND COMPANY (US) 2020-07-07 US disclosed
EP-3512851-A1 BETA-LACTAMASE INHIBITOR COMPOUNDS Entasis Therapeutics Limited (GB) 2019-07-24 EP disclosed
US-20180334701-A1 METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES BECTON DICKINSON CO (US) 2018-11-22 US disclosed
EP-3347008-A1 BETA-LACTAMASE INHIBITORS Venatorx Pharmaceuticals, Inc. (US) 2018-07-18 EP disclosed
WO-2018053215-A1 BETA-LACTAMASE INHIBITOR COMPOUNDS ENTASIS THERAPEUTICS LIMITED (GB) 2018-03-22 WO disclosed
US-9902989-B2 Methods for the detection of beta-lactamases BECTON, DICKINSON AND COMPANY (US) 2018-02-27 US disclosed
US-20090117601-A1 METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES BECTON, DICKINSON AND COMPANY 2009-05-07 US disclosed
EP-2038411-A1 MODIFIED BETA-LACTAMASE AND METHOD FOR ITS PREPARATION Ipsat Therapies Oy (FI) 2009-03-25 EP disclosed
EP-1913137-A1 SERINE BETA-LACTAMASE-LIKE / D-AIA CARBOXYPEPTIDASE-LIKE PROTEIN Ares Trading S.A. (CH) 2008-04-23 EP disclosed
WO-2007147945-A1 MODIFIED BETA-LACTAMASE AND METHOD FOR ITS PREPARATION IPSAT THERAPIES OY (FI) 2007-12-27 WO disclosed
WO-2007010283-A1 SERINE BETA-LACTAMASE-LIKE / D-ALA CARBOXYPEPTIDASE-LIKE PROTEIN ARES TRADING S.A. (CH) 2007-01-25 WO disclosed
EP-1263987-A2 RANDOM TRUNCATION AND AMPLIFICATION OF NUCLEIC ACID Genopsys, Inc. (US) 2002-12-11 EP disclosed
EP-1224277-A1 RANDOM MUTAGENESIS AND AMPLIFICATION OF NUCLEIC ACID Genopsys (US) 2002-07-24 EP disclosed
WO-2001012802-A9 RANDOM MUTAGENESIS AND AMPLIFICATION OF NUCLEIC ACID GENOPSYS (US) 2002-07-11 WO disclosed
WO-2001066798-A2 RANDOM TRUNCATION AND AMPLIFICATION OF NUCLEIC ACID GENOPSYS, INC. (US) 2001-09-13 WO disclosed
WO-2001012802-A1 RANDOM MUTAGENESIS AND AMPLIFICATION OF NUCLEIC ACID GENOPSYS (US) 2001-02-22 WO disclosed