SCHEMBL288510

SCHEMBL288510

NC(CC(=O)O)CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.50
GABRR1 P24046 2/20 0.48
LMNA P02545 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.45
ENPEP Q07075 4/20 0.42
ANPEP P15144 3/20 0.42
GLRA1 P23415 1/20 0.41
SLC6A9 P48067 1/20 0.41
OR51E2 Q9H255 1/20 0.41
TSHR P16473 1/20 0.41
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
GABRA2 P47869 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28799207 0.97 SLC22A6 (0.47) SLC22A6GABRR1LMNATDP1SMN1; SMN2
SCHEMBL6734053 0.97 SLC22A6 (0.47) SLC22A6GABRR1LMNATDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL7372643 0.97 SLC22A6 (0.47) SLC22A6GABRR1LMNATDP1SMN1; SMN2
Acetic Acid SCHEMBL2595033 0.91 SLC22A6 (0.43) SLC22A6GABRR1LMNATDP1SMN1; SMN2
SCHEMBL10142141 0.88 SLC22A6 (0.41) SLC22A6GABRR1LMNATDP1SMN1; SMN2
SCHEMBL288572 0.88 SLC22A6 (0.41) SLC22A6GABRR1LMNATDP1SMN1; SMN2
SCHEMBL19405330 0.88 SLC22A6 (0.41) SLC22A6GABRR1LMNATDP1SMN1; SMN2
SCHEMBL18265152 0.86 TDP1 (0.43) SLC22A6GABRR1LMNATDP1SMN1; SMN2
SCHEMBL4335769 0.84
SCHEMBL4340953 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 914 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737477-A2 HEPCIDIN MIMETICS FOR TREATMENT OF HEREDITARY HEMOCHROMATOSIS Protagonist Therapeutics, Inc. (US) 2026-05-06 EP claimed
EP-4706671-A2 CONJUGATED HEPCIDIN MIMETICS Protagonist Therapeutics, Inc. (US) 2026-03-11 EP claimed
US-20250360187-A1 HEPCIDIN MIMETICS FOR TREATMENT OF SICKLE CELL DISEASE PROTAGONIST THERAPEUTICS, INC. (US) 2025-11-27 US claimed
WO-2025217074-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2025-10-16 WO claimed
US-20250277012-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. 2025-09-04 US claimed
US-12378328-B2 Biohybrid peptidoglycan oligomers NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-08-05 US claimed
CN-117383660-B Graphene-based composite electrode and preparation method and application thereof 南京理工大学 2025-05-23 CN claimed
CN-119930947-A Alkali-soluble thickener, and preparation method and application thereof 苏州博纳化学科技有限公司 2025-05-06 CN claimed
WO-2025044828-A9 USE AND COMPOSITION OF POSTBIOTIC OF LACTOBACILLUS PARACASEI ET-22 内蒙古伊利实业集团股份有限公司 2025-04-03 WO claimed
CN-119708088-A Disaccharide-acylhydrazone or disaccharide-hydrazide linker, sugar engineering antibody based on same, sugar chain fixed-point antibody-drug conjugate and application 上海糖岭生物医药有限责任公司 2025-03-28 CN claimed
EP-1276732-A1 AMIDES OF R-2-(AMINOARYL)-PROPIONIC ACIDS FOR USE IN THEPREVENTION OF LEUCOCYTE ACTIVATION\ Dompé S.P.A. (IT) 2003-01-22 EP claimed
EP-1255726-A2 (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8 INDUCED CHEMIOTAXIS OF NEUTROPHILS Dompé S.P.A. (IT) 2002-11-13 EP claimed
WO-2001079189-A2 'AMIDES OF R-2-(AMINOARYL)-PROPIONIC ACIDS FOR USE IN THEPREVENTION OF LEUCOCYTE ACTIVATION' Dompé S.p.A. (IT) 2001-10-25 WO claimed
WO-2001058852-A2 (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8-INDUCED CHEMIOTAXIS OF NEUTROPHILS Dompé S.p.A. (IT) 2001-08-16 WO claimed
EP-1117677-A1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF Statens Serum Institut (DK) 2001-07-25 EP claimed
WO-2000018791-A1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF STATENS SERUM INSTITUT (DK) 2000-04-06 WO claimed
EP-0050799-B1 NEW PROCESSES FOR THE PRODUCTION OF DI-ALKYL ESTERS AND OPTICALLY ACTIVE MONO-ALKYL ESTERS OF 3-AMINOGLUTARIC ACID ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1984-12-19 EP claimed
US-4415657-A USING MICRORGANISMS FOR THE STEREOSPECIFIC HYDROGENOLYSIS OF THE DIALKYL B-PROTECTED AMINO ESTER KANEGAFUCHI CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 1983-11-15 US claimed
EP-0050799-A1 New processes for the production of di-alkyl esters and optically active mono-alkyl esters of 3-aminoglutaric acid ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1982-05-05 EP claimed
US-4246033-A REACTIVE COLORLESS COMPOUND AND A COLDRED COMPOUND OR DYE PELIKAN A.G. (CH) 1981-01-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378328-B2 Biohybrid peptidoglycan oligomers NOD2, DDOST, CD14 SLC22A6 1316/4885GABRR1 3817/4885LMNA 1245/4885
US-20250277012-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF SLC22A6 693/4885GABRR1 3859/4885LMNA 2431/4885
US-20250360187-A1 HEPCIDIN MIMETICS FOR TREATMENT OF SICKLE CELL DISEASE HAMP, HBG1, HBG2 SLC22A6 302/4885GABRR1 2683/4885LMNA 1752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.