Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.43 |
| ▸ | POLG | P54098 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338371 | 0.84 | POLB (0.61) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL12222460 | 0.84 | POLB (0.61) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL8627864 | 0.84 | POLB (0.63) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL4939418 | 0.84 | POLB (0.60) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL17182202 | 0.83 | POLB (0.64) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL338182 | 0.83 | LMNA (0.59) | P2RY2LMNATHRBMTORMDM2 | |
| SCHEMBL5709961 | 0.83 | POLB (0.59) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL7012047 | 0.83 | POLB (0.55) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL1763156 | 0.82 | POLB (0.61) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL13169192 | 0.82 | POLB (0.58) | POLBP2RY2P2RY4P2RY6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097711-B2 | nucleoside monomers protected with thioether substituted aryl carbonate protecting groups; oligonucleotides, using such protected nucleoside monomer monomers, as well as nucleic acids | AGILENT TECHNOLOGIES, INC. (US) | 2012-01-17 | — | — | US | disclosed |