Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.43 |
| ▸ | DRD3 | P35462 | 9/20 | 0.43 |
| ▸ | DRD4 | P21917 | 6/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788728 | 0.92 | DRD2 (0.41) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL3388370 | 0.91 | DRD2 (0.41) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL3390892 | 0.90 | DRD2 (0.40) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL3389944 | 0.87 | DRD2 (0.46) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL5222458 | 0.80 | MAPT (0.37) | DRD2DRD3DRD4MAPTPKM | |
| SCHEMBL6343702 | 0.78 | DRD3 (0.66) | DRD2DRD3DRD4 | |
| SCHEMBL7117724 | 0.77 | DRD2 (0.66) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL3390524 | 0.76 | DRD2 (0.43) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL6593135 | 0.76 | DRD2 (0.42) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL3387809 | 0.75 | DRD2 (0.46) | DRD2DRD3DRD4HTR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453805-B1 | 4-PIPERIDINYL ALKYLAMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2010-12-22 | — | — | EP | disclosed |