⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16282512 | 0.94 | — | — | |
| SCHEMBL10951056 | 0.80 | — | — | |
| SCHEMBL14750254 | 0.79 | — | — | |
| SCHEMBL7264130 | 0.79 | — | — | |
| SCHEMBL11337609 | 0.77 | — | — | |
| Phosphonic Acid SCHEMBL21060858 | 0.76 | — | — | |
| SCHEMBL4532459 | 0.76 | — | — | |
| SCHEMBL29592 | 0.75 | — | — | |
| Acetone SCHEMBL11333841 | 0.73 | LMNA (0.43) | — | |
| Ethane SCHEMBL269650 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309364-A | Diphosphonates | SYMPHAR S.A. (CH) | 1982-01-05 | — | — | US | claimed |
| US-12070746-B2 | Method of osteogenic differentiation in microfluidic tissue culture systems | EMULATE, Inc. (US) | 2024-08-27 | — | — | US | disclosed |
| US-12042791-B2 | Method of osteogenic differentiation in microfluidic tissue culture systems | CEDARS-SINAI MEDICAL CENTER (US) | 2024-07-23 | — | — | US | disclosed |
| CN-114730871-A | Electrolyte, lithium-sulfur secondary battery and assembly | 学校法人关西大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114258415-A | Polymer compounds containing phosphonate flame retardants | 化学制造布敦海姆两合公司 | 2022-03-29 | — | — | CN | disclosed |
| EP-3085390-B1 | COMPOUND FOR BONE SCANNING AND USE THEREOF | TAIWAN HOPAX CHEMS MFG CO LTD (TW) | 2020-02-26 | — | — | EP | disclosed |
| CN-106687823-B | The quantification system and storage medium of nuclear medicine image data | 公立大学法人横滨市立大学 | 2019-05-17 | — | — | CN | disclosed |
| CN-106065021-B | Compounds for bone scanning and uses thereof | 聚和国际股份有限公司 | 2019-02-19 | — | — | CN | disclosed |
| US-9828398-B2 | Compound for bone scanning and use thereof | TAIWAN HOPAX CHEMS. MFG. CO., LTD. (TW) | 2017-11-28 | — | — | US | disclosed |
| CN-106065021-A | Compounds for bone scanning and uses thereof | 聚和国际股份有限公司 | 2016-11-02 | — | — | CN | disclosed |
| EP-0561948-B1 | PHOSPHONIC ACID DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | UPJOHN CO (US) | 1995-04-05 | — | — | EP | disclosed |
| EP-0622373-A1 | Phosphonic acid derivatives useful as anti-inflammatory agents | THE UPJOHN COMPANY (US) | 1994-11-02 | — | — | EP | disclosed |
| US-5360797-A | Bisphosphonic acid derivatives useful as anti-arthritic agents | THE UPJOHN COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| US-5298498-A | Antiarthritic agents | THE UPJOHN COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0561948-A1 | PHOSPHONIC ACID DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS. | UPJOHN CO (US) | 1993-09-29 | — | — | EP | disclosed |
| EP-0531597-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| WO-1992010504-A2 | PHOSPHONIC ACID DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1992-06-25 | — | — | WO | disclosed |
| US-4877603-A | ANTICALCULUS AND ANTIPLAQUE COMPOSITION CONTAINING A GEMINAL DIPHOSPHONATE POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 1989-10-31 | — | — | US | disclosed |
| EP-0321233-A1 | Oral compositions | THE PROCTER & GAMBLE COMPANY (US) | 1989-06-21 | — | — | EP | disclosed |
| US-4416877-A | Anti-atherosclerotic pharmaceutical compositions containing diphosphonate compounds | SYMPHAR S.A. (CH) | 1983-11-22 | — | — | US | disclosed |