Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25833199 | 1.00 | HTT (0.44) | HTTLMNAKCNK3POLBSPHK1 | |
| SCHEMBL3740451 | 0.94 | HTT (0.49) | HTTLMNAKCNK3POLBSPHK1 | |
| SCHEMBL3276057 | 0.94 | HTT (0.49) | HTTLMNAKCNK3POLBSPHK1 | |
| SCHEMBL5216741 | 0.94 | HTT (0.49) | HTTLMNAKCNK3POLBSPHK1 | |
| SCHEMBL2563563 | 0.85 | LMNA (0.38) | HTTLMNAKCNK3POLBSPHK1 | |
| SCHEMBL16106745 | 0.84 | HTT (0.40) | HTTLMNAPOLBSPHK1SMN1; SMN2 | |
| SCHEMBL3969870 | 0.84 | LMNA (0.52) | HTTLMNAKCNK3POLBSPHK1 | |
| SCHEMBL1466679 | 0.84 | HTT (0.40) | HTTLMNAPOLBSPHK1SMN1; SMN2 | |
| SCHEMBL20143218 | 0.84 | LMNA (0.52) | HTTLMNAKCNK3POLBSPHK1 | |
| SCHEMBL1466682 | 0.84 | HTT (0.40) | HTTLMNAPOLBSPHK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167492-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | Hanmi Pharm. Co., Ltd. (KR) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008150118-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | HANMI PHARM. CO., LTD. (KR) | 2008-12-11 | — | — | WO | disclosed |