Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28499595 | 0.94 | KDM4E (0.56) | GAANPSR1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL29226837 | 0.94 | GAA (0.56) | GAANPSR1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL12412550 | 0.90 | SMN1; SMN2 (0.65) | GAANPSR1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL5321792 | 0.89 | GAA (0.60) | GAANPSR1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL5279675 | 0.85 | GAA (0.60) | GAANPSR1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11815554 | 0.84 | GAA (0.72) | GAANPSR1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL12227872 | 0.83 | SMN1; SMN2 (0.54) | GAASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL11550281 | 0.82 | GAA (0.70) | GAANPSR1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9267668 | 0.82 | GAA (0.70) | GAANPSR1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL1107148 | 0.82 | GAA (0.70) | GAANPSR1SMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954741-B1 | DIHYDROXY AROMATIC COMPOUNDS, METHODS FOR PREPARATION POLYMERS MADE THEREFROM, AND METHOD OF POLYMER PREPARATION | SABIC INNOVATIVE PLASTICS IP (NL) | 2010-12-22 | — | — | EP | disclosed |
| EP-1954741-A1 | DIHYDROXY AROMATIC COMPOUNDS, METHODS FOR PREPARATION POLYMERS MADE THEREFROM, AND METHOD OF POLYMER PREPARATION | General Electric Company (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007064608-A1 | DIHYDROXY AROMATIC COMPOUNDS, METHODS FOR PREPARATION POLYMERS MADE THEREFROM, AND METHOD OF POLYMER PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2007-06-07 | — | — | WO | disclosed |
| US-7183431-B1 | Dihydroxy aromatic compounds and methods for preparation | GENERAL ELECTRIC COMPANY (US) | 2007-02-27 | — | — | US | disclosed |
| US-6613769-B1 | Incubating samples with enzyme inhibitors, then determining complexes formed; medical diagnosis; therapy for allergies and inflammation | Max-Planck-Gesellschaft zur Föderung der Wissenschaften. e.V. (DE) | 2003-09-02 | — | — | US | disclosed |
| US-6489327-B1 | TREATING A DISEASE SUSCEPTIBLE TO TRYPTASE INHIBITION SUCH AS ASTHMA, INFLAMMATORY BOWEL DISEASE, PSORIASIS OR RHINITIS | MAX-PLANCK-GESELLSCHAFT ZUR FORDRUNGDER WISENSCHAFTEN, E.V. (DE) | 2002-12-03 | — | — | US | disclosed |