Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | ATF4 | P18848 | 4/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | FADS1 | O60427 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355815 | 0.71 | CYP19A1 (0.36) | ADAMTS5ATF4 | |
| SCHEMBL3354481 | 0.70 | ATF4 (0.41) | ADAMTS5ATF4 | |
| SCHEMBL3432233 | 0.70 | GRIN1 (0.46) | — | |
| SCHEMBL3354901 | 0.70 | CYP19A1 (0.38) | ADAMTS5ATF4 | |
| SCHEMBL3353721 | 0.68 | DRD4 (0.39) | ADAMTS5ATF4GHSR | |
| SCHEMBL3355002 | 0.64 | CCR1 (0.54) | — | |
| SCHEMBL3355449 | 0.64 | CCR1 (0.54) | — | |
| SCHEMBL3352352 | 0.64 | KDM4E (0.42) | — | |
| SCHEMBL3354266 | 0.64 | AIMP2 (0.49) | ADAMTS5ATF4 | |
| SCHEMBL13308188 | 0.64 | ATF4 (0.58) | ADAMTS5ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | claimed |