SCHEMBL3388581

SCHEMBL3388581

CO[SiH](OC)C(CCCN)C1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.35
TP53 P04637 1/20 0.33
MEN1 O00255 1/20 0.33
MITF O75030 1/20 0.33
KMT2A Q03164 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SHBG P04278 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6346821 0.84 SHBG (0.36) SIGMAR1SHBG
SCHEMBL7939623 0.83 SHBG (0.35) EPHX1SIGMAR1SHBG
SCHEMBL8976903 0.81 TSHR (0.33) SHBG
SCHEMBL7926274 0.80 SHBG (0.39) EPHX1SMN1; SMN2SHBG
SCHEMBL8852159 0.78 SHBG (0.35) SHBG
SCHEMBL819315 0.76 SHBG (0.46) EPHX1TP53KDM4ESHBG
SCHEMBL10009772 0.76 SHBG (0.46) EPHX1TP53KDM4ESHBG
SCHEMBL819916 0.74 SHBG (0.43) KDM4ESHBG
SCHEMBL6910647 0.73 SHBG (0.34) EPHX1SMN1; SMN2SHBG
SCHEMBL6911017 0.73 SHBG (0.34) EPHX1SMN1; SMN2SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8202928-B2 Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof CONTINENTAL AUTOMOTIVE SYSTEMS, INC (US) 2012-06-19 US claimed
US-20100038859-A1 METHOD OF PREPARING AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US claimed
US-20100038856-A1 AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US claimed
WO-2020241542-A1 ANTIFOULING COATING COMPOSITION 日東化成株式会社 2020-12-03 WO disclosed
US-8202928-B2 Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof CONTINENTAL AUTOMOTIVE SYSTEMS, INC (US) 2012-06-19 US disclosed
US-20100038859-A1 METHOD OF PREPARING AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US disclosed
US-20100038856-A1 AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US disclosed