SCHEMBL338867

SCHEMBL338867

CC(C)c1cc(C(C)C)cc(C(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
FABP3 P05413 2/20 0.43
FABP4 P15090 2/20 0.43
FABP5 Q01469 1/20 0.42
LMNA P02545 1/20 0.41
TRPA1 O75762 1/20 0.39
PTGS1 P23219 1/20 0.39
CACNA1C Q13936 1/20 0.39
HTT P42858 3/20 0.38
ALDH1A1 P00352 2/20 0.38
ALOX12 P18054 2/20 0.38
GAA P10253 1/20 0.38
HIF1A Q16665 1/20 0.38
TYR P14679 4/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
KDM4E B2RXH2 2/20 0.35
HDAC4 P56524 2/20 0.35
HDAC8 Q9BY41 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28414081 0.96 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
Hydrogen Sulfide SCHEMBL28283354 0.96 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
Hydrochloric Acid SCHEMBL5790729 0.96 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL23202783 0.96 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
Calcium SCHEMBL29750665 0.96 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL23202734 0.96 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL3234036 0.96 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL29415630 0.96 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
Hydrogen Peroxide SCHEMBL3271546 0.92 FABP3 (0.52) GABRA1GABRB2FABP3FABP4FABP5
Hydrogen Peroxide SCHEMBL3267226 0.92 FABP3 (0.52) GABRA1GABRB2FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1966 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739724-A1 MULTI-COMPONENT RESIN SYSTEM COMPRISING AT LEAST ONE PLASTICISER, MORTAR COMPOSITION BASED ON ISOCYANATE-AMINE ADDUCTS, AND METHOD AND USE OF THE MULTI-COMPONENT RESIN SYSTEM FOR FASTENING CONSTRUCTION ELEMENTS Hilti Aktiengesellschaft (LI) 2026-05-13 EP claimed
US-12577236-B2 Processes for preparation of Tezacaftor LAURUS LABS LIMITED (IN) 2026-03-17 US claimed
CN-120059849-A Safflower pepper aromatic water and preparation method and application thereof 梅良屿 2025-05-30 CN claimed
CN-119909709-A Catalytic cracking auxiliary agent for resisting metal pollution and preparation method thereof 中国石油天然气股份有限公司 2025-05-02 CN claimed
CN-119909724-A Catalytic cracking auxiliary agent and preparation method and application thereof 中国石油天然气股份有限公司 2025-05-02 CN claimed
CN-119909666-A Composite binder and preparation method and application thereof 中国石油天然气股份有限公司 2025-05-02 CN claimed
CN-119909718-A Heavy oil cracking catalyst and preparation method thereof 中国石油天然气股份有限公司 2025-05-02 CN claimed
CN-119909743-A Catalytic cracking auxiliary agent and preparation method thereof 中国石油天然气股份有限公司 2025-05-02 CN claimed
CN-119909723-A Catalytic cracking auxiliary agent and preparation method thereof 中国石油天然气股份有限公司 2025-05-02 CN claimed
CN-119909741-A Catalytic cracking catalyst and preparation method thereof 中国石油天然气股份有限公司 2025-05-02 CN claimed
US-5004841-A Para-substitutions with crystalline acidic mordenite zeolite alkylation catalysts THE DOW CHEMICAL COMPANY (US) 1991-04-02 US claimed
WO-1991003517-A1 STABILIZATION OF POLY(ETHER KETONE KETONES) E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-21 WO claimed
US-4987171-A Heating with organic hydroperoxide E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-22 US claimed
US-4891448-A ACIDIC MORDENITE CATALYST THE DOW CHEMICAL COMPANY (US) 1990-01-02 US claimed
EP-0317907-A2 Alkylation of polycyclic aromatic compounds to alkylates enriched in the para-substituted isomers THE DOW CHEMICAL COMPANY (US) 1989-05-31 EP claimed
WO-1989000077-A1 LECITHIN GEL LUISI PIER LUIGI (CH) 1989-01-12 WO claimed
EP-0228095-A2 Process for the preparation of olefinic silanes and siloxanes UNION CARBIDE CORPORATION (US) 1987-07-08 EP claimed
US-4668812-A Process for the preparation of olefinic silanes and siloxanes UNION CARBIDE CORPORATION (US) 1987-05-26 US claimed
US-4469899-A Process for producing phloroglucin SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-09-04 US claimed
US-4455440-A OXIDATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-06-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577236-B2 Processes for preparation of Tezacaftor CYP4A11, F9, CYP3A4 GABRA1 2106/4885GABRB2 2895/4885FABP3 4733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.