⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879865 | 0.73 | — | — | |
| SCHEMBL8634645 | 0.71 | — | — | |
| SCHEMBL5558515 | 0.71 | — | — | |
| SCHEMBL30716226 | 0.69 | — | — | |
| Carbon Dioxide SCHEMBL28132271 | 0.67 | — | — | |
| SCHEMBL2436975 | 0.65 | — | — | |
| SCHEMBL2436973 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL10418372 | 0.63 | — | — | |
| SCHEMBL29118924 | 0.63 | — | — | |
| SCHEMBL7053456 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161837-B2 | Benzofuran derivatives for the treatment of hepatitis C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200291002-A1 | BENZOFURAN DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2020-09-17 | — | — | US | disclosed |
| CN-106866460-B | A kind of Schiff bases Multifunction fluorescent probe and preparation method and application | 东南大学 | 2018-05-15 | — | — | CN | disclosed |
| WO-2017165233-A1 | BENZOFURAN DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-28 | — | — | WO | disclosed |
| CN-106866460-A | A kind of Schiff bases Multifunction fluorescent probe and preparation method and application | 东南大学 | 2017-06-20 | — | — | CN | disclosed |
| CN-106674219-A | Preparation method of Riociguat intermediate | 上海医药工业研究院 | 2017-05-17 | — | — | CN | disclosed |
| CN-101300012-B | Use of Diaminopyrimidine as P2X3 and P2x2/3 modulators in preparing medicine for treating respiratory diseases | HOFFMANN LA ROCHE | 2011-09-14 | — | — | CN | disclosed |
| EP-1521749-B8 | PHENYL-(4-(3-PHENYL-1H-PYRAZOL-4-YL)-PYRIMIDIN-2-Yl)-AMINE DERIVATIVES | NOVARTIS AG (CH) | 2010-12-22 | — | — | EP | disclosed |
| US-20100160324-A1 | PYRAZOLE DERIVATIVES AS THAT MODULATE THE ACTIVITY OF CDK, GSK AND AURORA KINASES | ASTEX THERAPEUTICS LIMITED (GB) | 2010-06-24 | — | — | US | disclosed |
| CN-101300012-A | Diaminopyrimidine as P2X3 and P2x2/3 modulators | ROCHE PALO ALTO LLC (CH) | 2008-11-05 | — | — | CN | disclosed |
| EP-1399440-A1 | 5-(2-AMINOPYRIMIDIN-4-YL)BENZISOXAZOLES AS PROTEIN KINASE INHIBITORS | Vertex Pharmaceuticals Incorporated (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2004005282-A1 | PHENYL-[4-(3-PHENYL-1H-PYRAZOL-4-YL)-PYRIMIDIN-2-Yl)-AMINE DERIVATIVES | NOVARTIS AG (CH) | 2004-01-15 | — | — | WO | disclosed |
| US-20040005637-A1 | Intermediate products, methods for their preparation and use thereof | BIOTAGE AB (SE) | 2004-01-08 | — | — | US | disclosed |
| WO-2003101933-A1 | INTERMEDIATE PRODUCTS, METHODS FOR THEIR PREPARATION AND USE THEREOF | PERSONAL CHEMISTRY I UPPSALA AB (SE) | 2003-12-11 | — | — | WO | disclosed |
| EP-1367045-A1 | Intermediate products, methods for their preparation and use thereof | Personal Chemistry i Uppsala AB (SE) | 2003-12-03 | — | — | EP | disclosed |
| US-20030191156-A1 | Beta3 adrenergic agonists | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT | 2003-10-09 | — | — | US | disclosed |
| EP-1303509-A1 | BETA3 ADRENERGIC AGONISTS | ELI LILLY AND COMPANY (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002102800-A1 | 5-(2-AMINOPYRIMIDIN-4-YL) BENZISOXAZOLES AS PROTEIN KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2002-12-27 | — | — | WO | disclosed |
| WO-2002006276-A1 | BETA3 ADRENERGIC AGONISTS | ELI LILLY AND COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |
| WO-1994029300-A1 | PYRAZOLE FUNGICIDES 3-SUBSTITUTED BY A HETEROCYCLIC RING | RHONE POULENC AGROCHIMIE (FR) | 1994-12-22 | — | — | WO | disclosed |