Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423893 | 0.88 | MAPK14 (0.62) | MAPK14MAPK13MAPK11MAPK12 | |
| SCHEMBL2956606 | 0.86 | MAPK14 (0.64) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL2953566 | 0.84 | MAPK14 (0.58) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL2959225 | 0.81 | MAPK14 (0.51) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL2956884 | 0.80 | MAPK14 (0.49) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL3174306 | 0.75 | MAPK14 (0.59) | MAPK14MAPK13MAPK11MAPK12 | |
| SCHEMBL4603225 | 0.74 | MAPK14 (0.51) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL4602243 | 0.74 | MAPK14 (0.60) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL3419400 | 0.73 | MAPK14 (0.56) | MAPK14MAPK13MAPK11MAPK12 | |
| Hydrochloric Acid SCHEMBL4602456 | 0.73 | MAPK14 (0.63) | MAPK14MAPK13MAPTMAPK11MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943243-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2010-12-29 | — | — | EP | disclosed |