Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.68 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.68 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.59 |
| ▸ | FLT1 | P17948 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392073 | 0.96 | ERBB2 (0.72) | EGFRERBB2FGFR1FLT1KDR | |
| SCHEMBL3434900 | 0.85 | EGFR (0.62) | EGFRERBB2FGFR1FLT1KDR | |
| SCHEMBL3395009 | 0.84 | EGFR (0.65) | EGFRERBB2FGFR1FLT1KDR | |
| SCHEMBL4887398 | 0.82 | ERBB2 (0.86) | EGFRERBB2 | |
| SCHEMBL3390827 | 0.82 | ERBB2 (0.78) | EGFRERBB2 | |
| SCHEMBL3391499 | 0.82 | ERBB2 (0.73) | EGFRERBB2FGFR1FLT1KDR | |
| Hydrochloric Acid SCHEMBL4876811 | 0.82 | ERBB2 (0.85) | EGFRERBB2 | |
| SCHEMBL9883167 | 0.82 | EGFR (0.84) | EGFRERBB2FGFR1FLT1KDR | |
| SCHEMBL3695904 | 0.81 | EGFR (0.86) | EGFRERBB2 | |
| SCHEMBL3695899 | 0.81 | EGFR (0.86) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167492-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | Hanmi Pharm. Co., Ltd. (KR) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008150118-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | HANMI PHARM. CO., LTD. (KR) | 2008-12-11 | — | — | WO | disclosed |