Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 3/20 | 0.72 |
| ▸ | EGFR | P00533 | 17/20 | 0.70 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.61 |
| ▸ | RET | P07949 | 1/20 | 0.61 |
| ▸ | MET | P08581 | 1/20 | 0.61 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.61 |
| ▸ | TEC | P42680 | 1/20 | 0.61 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.61 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.61 |
| ▸ | BTK | Q06187 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.61 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.60 |
| ▸ | FLT1 | P17948 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389179 | 0.96 | EGFR (0.68) | ERBB2EGFRFGFR1FLT1KDR | |
| SCHEMBL4887398 | 0.85 | ERBB2 (0.86) | ERBB2EGFRRIPK2RETMET | |
| SCHEMBL3390827 | 0.85 | ERBB2 (0.78) | ERBB2EGFRRIPK2RETMET | |
| Hydrochloric Acid SCHEMBL4876811 | 0.84 | ERBB2 (0.85) | ERBB2EGFRRIPK2RETMET | |
| SCHEMBL3434900 | 0.84 | EGFR (0.62) | ERBB2EGFREPHB4FGFR1FLT1 | |
| SCHEMBL4887927 | 0.84 | ERBB2 (1.00) | ERBB2EGFRRIPK2RETEPHB2 | |
| SCHEMBL3391929 | 0.84 | EGFR (0.73) | ERBB2EGFRRIPK2RETMET | |
| SCHEMBL5207429 | 0.83 | EGFR (0.85) | ERBB2EGFRRIPK2RETMET | |
| SCHEMBL3391499 | 0.83 | ERBB2 (0.73) | ERBB2EGFRRIPK2RETMET | |
| SCHEMBL3395487 | 0.83 | ERBB2 (0.77) | ERBB2EGFRRIPK2RETMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167492-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | Hanmi Pharm. Co., Ltd. (KR) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008150118-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | HANMI PHARM. CO., LTD. (KR) | 2008-12-11 | — | — | WO | disclosed |