Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.61 |
| ▸ | HTR2B | P41595 | 14/20 | 0.61 |
| ▸ | HTR2A | P28223 | 13/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1262193 | 0.99 | HTR2C (0.60) | HTR2CHTR2BHTR2AHTR1ADRD2 | |
| SCHEMBL3389240 | 0.78 | HTR2A (0.37) | HTR2CHTR2BHTR2A | |
| SCHEMBL3388287 | 0.78 | HTR2C (0.53) | HTR2CHTR2BHTR2AHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL1262759 | 0.77 | HTR2A (0.36) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL1262699 | 0.77 | HTR2A (0.52) | HTR2CHTR2BHTR2AHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL1262608 | 0.76 | HTR2A (0.36) | HTR2CHTR2BHTR2A | |
| SCHEMBL300642 | 0.76 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1ADRD2 | |
| SCHEMBL3421612 | 0.75 | DPP4 (0.36) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL183534 | 0.75 | HTR2C (0.98) | HTR2CHTR2BHTR2AHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL1262905 | 0.74 | DPP4 (0.36) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863812-B1 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD (KR) | 2010-07-14 | — | — | EP | disclosed |