Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | HTR2B | P41595 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1262759 | 0.98 | HTR2A (0.36) | HTR2AHTR2CHTR2BSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1262608 | 0.85 | HTR2A (0.36) | HTR2AHTR2CHTR2BSMN1; SMN2L3MBTL1 | |
| SCHEMBL3421612 | 0.84 | DPP4 (0.36) | HTR2AHTR2CHTR2BSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1262905 | 0.82 | DPP4 (0.36) | HTR2AHTR2CHTR2BSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1262892 | 0.81 | HTR2A (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL3393508 | 0.80 | DPP4 (0.38) | HTR2AHTR2CHTR2BSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1262187 | 0.79 | DPP4 (0.37) | HTR2AHTR2CHTR2BSMN1; SMN2L3MBTL1 | |
| SCHEMBL1967719 | 0.79 | HTR2A (0.34) | HTR2AHTR2CHTR2BSMN1; SMN2L3MBTL1 | |
| SCHEMBL3389339 | 0.78 | HTR2C (0.61) | HTR2AHTR2CHTR2B | |
| SCHEMBL1970467 | 0.78 | HTR2A (0.36) | HTR2AHTR2CHTR2BSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863812-B1 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD (KR) | 2010-07-14 | — | — | EP | disclosed |