Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554602 | 0.83 | TDP1 (0.75) | TDP1L3MBTL1TSHRGPR35APEX1 | |
| SCHEMBL3986801 | 0.82 | TDP1 (0.47) | TDP1L3MBTL1TSHRGPR35SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL28004578 | 0.80 | TDP1 (0.70) | TDP1L3MBTL1TSHRGPR35APEX1 | |
| SCHEMBL33666 | 0.79 | TDP1 (1.00) | TDP1L3MBTL1TSHRGPR35SMN1; SMN2 | |
| SCHEMBL1585523 | 0.79 | TDP1 (1.00) | TDP1L3MBTL1TSHRGPR35SMN1; SMN2 | |
| SCHEMBL28117 | 0.77 | HSD17B10 (0.54) | TDP1TSHRGPR35SMN1; SMN2ERN1 | |
| SCHEMBL29614987 | 0.77 | HSD17B10 (0.54) | TDP1TSHRGPR35SMN1; SMN2ERN1 | |
| SCHEMBL15869336 | 0.77 | TDP1 (0.66) | TDP1L3MBTL1TSHRGPR35SMN1; SMN2 | |
| SCHEMBL4962627 | 0.77 | TDP1 (0.66) | TDP1L3MBTL1TSHRGPR35APEX1 | |
| SCHEMBL6500391 | 0.77 | TDP1 (0.67) | TDP1L3MBTL1TSHRGPR35SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2223133-A1 | MAGNETIC RESONANCE SYSTEM WITH IMPLANTABLE COMPONENTS AND METHODS OF USE THEREOF | T2 Biosystems, Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009085214-A1 | MAGNETIC RESONANCE SYSTEM WITH IMPLANTABLE COMPONENTS AND METHODS OF USE THEREOF | T2 BIOSYSTEMS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |