Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398188 | 0.87 | TDP1 (0.56) | TDP1L3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL15971486 | 0.83 | TDP1 (0.59) | TDP1L3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL3389366 | 0.82 | TDP1 (0.65) | TDP1L3MBTL1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL15971290 | 0.81 | CA12 (0.67) | TDP1L3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL50994 | 0.81 | TSHR (0.54) | TDP1L3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL283363 | 0.81 | TDP1 (0.68) | TDP1L3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL2479195 | 0.80 | ERN1 (0.55) | TDP1L3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL13983247 | 0.79 | MAPT (0.49) | TDP1L3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL1612194 | 0.79 | MAPT (0.59) | TDP1L3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL4099183 | 0.79 | TDP1 (0.49) | TDP1L3MBTL1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061756-A2 | 2-AMINOCARBONYLPHENYLAMINO-2-PHENILACETAMIDES AS FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | Brystol-Myers Squibb Company (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2007146719-A2 | 2-AMINOCARBONYLPHENYLAMINO-2-PHENYLACETAMIDES AS FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-21 | — | — | WO | disclosed |