Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 5/20 | 0.53 |
| ▸ | CDK2 | P24941 | 5/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | TUBB8B | A6NNZ2 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388417 | 0.89 | CCNA2 (0.66) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL3389148 | 0.87 | CDK2 (0.49) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL3387481 | 0.86 | CDK5 (0.65) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL3386123 | 0.85 | MEN1 (0.52) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL3386135 | 0.85 | CDK2 (0.51) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL3384731 | 0.83 | CDK2 (0.53) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL28761671 | 0.83 | CDK5 (0.52) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL3382774 | 0.82 | CDK5 (0.68) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL3389151 | 0.81 | CDK5 (0.49) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL3389651 | 0.81 | CDK5 (0.59) | CCNA2CDK2CDK5CDK5R1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771424-B1 | NOVEL 2,4-DIAMINOTHIAZOL-5-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-12-15 | — | — | EP | claimed |