SCHEMBL33898

SCHEMBL33898

CN(C)c1cccc(NC(N)=O)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
ALDH1A1 P00352 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
GAA P10253 2/20 0.56
ALOX15 P16050 1/20 0.56
MAPK1 P28482 1/20 0.55
BCHE P06276 1/20 0.51
ACHE P22303 1/20 0.51
KCNK3 O14649 1/20 0.50
HIF1A Q16665 1/20 0.50
HDAC6 Q9UBN7 2/20 0.49
PNPLA2 Q96AD5 1/20 0.49
NPC1 O15118 1/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
TSHR P16473 1/20 0.49
NFKB1 P19838 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29356607 1.00 MAPT (0.57) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL28877258 0.92 ALDH1A1 (0.57) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL27507634 0.86 MAPT (0.55) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL24166779 0.85 MEN1 (0.46) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL8999455 0.84 ALDH1A1 (0.59) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL27389810 0.83 HDAC4 (0.46) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL29639390 0.83 MAPT (0.45) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL4864978 0.83 MEN1 (0.45) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL20313975 0.82 HDAC6 (0.69) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL11883991 0.82 ALDH1A1 (0.62) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3399 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12383482-B2 Hair coloring compositions WELLA GERMANY GMBH (DE) 2025-08-12 US claimed
EP-4251285-B1 HAIR COLORING COMPOSITIONS WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2024-09-04 EP claimed
US-20240024218-A1 HAIR COLORING COMPOSITIONS WELLA GERMANY GMBH (DE) 2024-01-25 US claimed
CN-117396185-A Hair dyeing composition 威娜国际运营瑞士责任有限公司 2024-01-12 CN claimed
EP-4251285-A1 HAIR COLORING COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2023-10-04 EP claimed
US-11555017-B2 Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres L'OREAL (FR) 2023-01-17 US claimed
US-20220183940-A1 DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES L'OREAL (FR) 2022-06-16 US claimed
WO-2022112473-A1 HAIR COLORING COMPOSITIONS WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2022-06-02 WO claimed
EP-3946217-A1 DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES L'OREAL (FR) 2022-02-09 EP claimed
CN-112089633-A Oxidation dyeing method 莱雅公司 2020-12-18 CN claimed
US-20030070239-A1 Agent and method for dyeing keratin fibers HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2003-04-17 US claimed
WO-2002076417-A1 OXIDATION DYEING COMPOSITION CONTAINING AT LEAST ONE 3-AMINO PYRAZOLO-[1,5-A]-PYRIDINE OXIDATION BASE AND AT LEAST ONE PARTICULAR PYRAZOLOTRIAZOLE COUPLING AGENT L'OREAL (FR) 2002-10-03 WO claimed
WO-2002076416-A1 OXIDATION DYEING COMPOSITION CONTAINING 3-AMINO PYRAZOLO-[1,5-A] PYRIDINE AND 2-AMINO-3-HYDROXY PYRIDINE L'OREAL (FR) 2002-10-03 WO claimed
WO-2002076419-A1 OXIDATION DYEING COMPOSITION CONTAINING 3-AMINO PYRAZOLO-[1,5-A]-PYRIDINE AND ONE AMINOPHENOL COUPLING AGENT L'OREAL (FR) 2002-10-03 WO claimed
WO-2002076418-A1 OXIDATION DYEING COMPOSITION 3-AMINO PYRAZOLO-[1,5-A]-PYRIDINE AND ONE PYRAZOLOTRIAZOLE COUPLING AGENT L'OREAL (FR) 2002-10-03 WO claimed
US-5961667-A Dyeing hair with compositions which contain oxidation dye precursor compounds, alkaline earth metal peroxides and inorganic or organic acids WELLA AG (DE) 1999-10-05 US claimed
US-5718731-A Oxidation hair dye composition based on 4,5-diaminopyrazole and m-phenylenediamine derivatives WELLA AKTIENGESELLSCHAFT (DE) 1998-02-17 US claimed
US-5696110-A ANTIULCER AGENTS MERCK, SHARP & DOHME, LTD. (GB) 1997-12-09 US claimed
US-5686449-A 1,5-benzodiazepines useful as gastrinor CCK-antagonists GLAXO WELLCOME S.P.A. (IT) 1997-11-11 US claimed
EP-0692245-B1 Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives WELLA AG (DE) 1997-05-02 EP claimed