⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038204 | 0.79 | — | — | |
| SCHEMBL2995 | 0.67 | — | — | |
| SCHEMBL269360 | 0.67 | — | — | |
| SCHEMBL365283 | 0.67 | — | — | |
| SCHEMBL6963539 | 0.64 | — | — | |
| SCHEMBL1483243 | 0.64 | — | — | |
| SCHEMBL121159 | 0.64 | — | — | |
| SCHEMBL28120931 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL27660045 | 0.64 | — | — | |
| SCHEMBL77707 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046713-A2 | METHODS FOR PREPARING HETEROCYCLIC RINGS | ISIS INNOVATION (GB) | 2010-04-29 | — | — | WO | claimed |
| WO-2010046713-A2 | METHODS FOR PREPARING HETEROCYCLIC RINGS | ISIS INNOVATION (GB) | 2010-04-29 | — | — | WO | disclosed |
| EP-0127234-B1 | A RETRO-INVERSO ANALOGUE OF THE (5-14) DECAPEPTIDE OF EQUINE ANGIOTENSINOGEN, AS A SPECIFIC RENIN INHIBITOR WITH HIGH RESISTANCE TO ENZYMATIC HYDROLYSIS | ENI-Ente Nazionale Idrocarburi (IT) | 1987-09-23 | — | — | EP | disclosed |
| US-4560505-A | HYPOTENSIVE AGENTS | ENI - ENTE NAZIONALE IDROCARBURI (IT) | 1985-12-24 | — | — | US | disclosed |
| EP-0127234-A2 | A retro-inverso analogue of the (5-14) decapeptide of equine angiotensinogen, as a specific renin inhibitor with high resistance to enzymatic hydrolysis | ENI-Ente Nazionale Idrocarburi (IT) | 1984-12-05 | — | — | EP | disclosed |