⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786587 | 0.69 | — | — | |
| SCHEMBL2995 | 0.67 | — | — | |
| SCHEMBL269360 | 0.67 | — | — | |
| SCHEMBL3389890 | 0.67 | — | — | |
| SCHEMBL9483250 | 0.65 | TSHR (0.30) | — | |
| SCHEMBL6963539 | 0.64 | — | — | |
| SCHEMBL1483243 | 0.64 | — | — | |
| SCHEMBL28120931 | 0.64 | — | — | |
| SCHEMBL121159 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL27660045 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851545-B | Synthetic process of Ledipasvir intermediate | 日照巴洛特药业有限公司 | 2022-09-20 | — | — | CN | claimed |
| EP-1546235-B1 | WATER-SOLUBLE POLYMER ALKANALS | NEKTAR THERAPEUTICS (US) | 2021-10-20 | — | — | EP | claimed |
| CN-112851545-A | Synthetic process of Ledipasvir intermediate | 日照巴洛特药业有限公司 | 2021-05-28 | — | — | CN | claimed |
| EP-2496570-B1 | PROCESS FOR THE PREPARATION OF 5-(2-AMINO-PYRIMIDIN-4-YL)-2-ARYL-1H-PYRROLE-3-CARBOXAMIDES | NERVIANO MEDICAL SCIENCES SRL (IT) | 2016-06-29 | — | — | EP | claimed |
| CN-102036983-B | Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h-pyrrole-3-carboxamides | NERVIANO MEDICAL SCIENCES SRL | 2014-02-19 | — | — | CN | claimed |
| CN-103421004-A | 5-azaindole preparation method | ASCEPION PHARMACEUTICALS INC | 2013-12-04 | — | — | CN | claimed |
| US-8592583-B2 | Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxamides | NERVIANO MEDICAL SCIENCES (IT) | 2013-11-26 | — | — | US | claimed |
| CN-102241588-B | Preparation method for (2Z,4E)11-methoxy-3,7,11-trimethyl-2,4-dodecadienoic acid isopropyl ester | SYNERGETICA CHANGZHOU CHEMICAL CO LTD | 2013-05-29 | — | — | CN | claimed |
| EP-2496570-A1 | PROCESS FOR THE PREPARATION OF 5-(2-AMINO-PYRIMIDIN-4-YL)-2-ARYL-1H-PYRROLE-3-CARBOXAMIDES | Nerviano Medical Sciences S.r.l. (IT) | 2012-09-12 | — | — | EP | claimed |
| CN-102666527-A | Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h-pyrrole-3-carboxamides | NERVIANO MEDICAL SCIENCES SRL (IT) | 2012-09-12 | — | — | CN | claimed |
| CN-1329427-C | Water soluble polymer alkanals | NEKTAR THERAPEUTICS CORP (US) | 2007-08-01 | — | — | CN | claimed |
| US-7157546-B2 | Polyoxyethylene glycol; purity, storage stability | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2007-01-02 | — | — | US | claimed |
| US-20060194940-A1 | 2-methylbutyraldehyde diethyl acetal end capped polyoxyethylene glycol; polyalkylene oxide, polyivnylpyrrolidone, polyvinyl alcohol, polyoxazoline etc. endcapped with polyetherpolyamine copolymers or oligomers covalently attached to diacetal tetramethylene group | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2006-08-31 | — | — | US | claimed |
| JP-2005538224-A | — | — | 2005-12-15 | — | — | JP | claimed |
| CN-1688631-A | Water soluble polymer alkanals | NEKTAR THERAPEUTICS AL CORP (US) | 2005-10-26 | — | — | CN | claimed |
| EP-1546235-A2 | WATER-SOLUBLE POLYMER ALKANALS | Nektar Therapeutics Al, Corporation (US) | 2005-06-29 | — | — | EP | claimed |
| CN-1197870-C | Preparation method and intermediate of erythromycin derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-04-20 | — | — | CN | claimed |
| US-20040116649-A1 | Polyoxyethylene glycol; purity, storage stability | NEKTAR THERAPEUTICS | 2004-06-17 | — | — | US | claimed |
| WO-2004022630-A2 | WATER-SOLUBLE POLYMER ALKANALS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2004-03-18 | — | — | WO | claimed |
| CN-1446224-A | Process for producing erythromycin derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-10-01 | — | — | CN | claimed |