Questiomycin B

Questiomycin B

SCHEMBL3389959

CCN(CC)CC.Nc1ccccc1O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.65
TSHR P16473 2/20 0.65
PRKCI P41743 1/20 0.46
ACHE P22303 1/20 0.44
ALDH1A1 P00352 7/20 0.44
KDM4E B2RXH2 4/20 0.44
HPGD P15428 4/20 0.44
HSD17B10 Q99714 5/20 0.43
HTR1A P08908 1/20 0.40
POLB P06746 3/20 0.39
MAPT P10636 3/20 0.39
APEX1 P27695 2/20 0.39
RECQL P46063 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 2/20 0.39
HTT P42858 2/20 0.39
KMT2A Q03164 2/20 0.39
THRB P10828 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Questiomycin B SCHEMBL8718526 0.86 ALOX15 (0.79) ALOX15TSHRALDH1A1KDM4EHPGD
Questiomycin B SCHEMBL10786495 0.84 ALOX15 (0.75) ALOX15TSHRALDH1A1KDM4EHPGD
Questiomycin B SCHEMBL27305569 0.84 ALOX15 (0.75) ALOX15TSHRALDH1A1KDM4EHPGD
Catechol SCHEMBL29648961 0.84 KDM4E (0.56) ALOX15TSHRPRKCIACHEALDH1A1
Catechol SCHEMBL27915952 0.84 KDM4E (0.56) ALOX15TSHRPRKCIACHEALDH1A1
Questiomycin B SCHEMBL27708789 0.81 ALOX15 (0.79) ALOX15TSHRALDH1A1KDM4EHPGD
Questiomycin B SCHEMBL27521296 0.81 ALOX15 (0.88) ALOX15TSHRALDH1A1KDM4EHPGD
Questiomycin B SCHEMBL24436 0.81
Questiomycin B SCHEMBL29430322 0.81
Questiomycin B SCHEMBL3999786 0.81 ALOX15 (1.00) ALOX15TSHRALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1954741-B1 DIHYDROXY AROMATIC COMPOUNDS, METHODS FOR PREPARATION POLYMERS MADE THEREFROM, AND METHOD OF POLYMER PREPARATION SABIC INNOVATIVE PLASTICS IP (NL) 2010-12-22 EP disclosed
CN-101346410-A Dihydroxy aromatic compounds, methods for preparation polymers made therefrom, and method of polymer preparation GEN ELECTRIC (US) 2009-01-14 CN disclosed
EP-1954741-A1 DIHYDROXY AROMATIC COMPOUNDS, METHODS FOR PREPARATION POLYMERS MADE THEREFROM, AND METHOD OF POLYMER PREPARATION General Electric Company (US) 2008-08-13 EP disclosed
WO-2007064608-A1 DIHYDROXY AROMATIC COMPOUNDS, METHODS FOR PREPARATION POLYMERS MADE THEREFROM, AND METHOD OF POLYMER PREPARATION GENERAL ELECTRIC COMPANY (US) 2007-06-07 WO disclosed
US-7183431-B1 Dihydroxy aromatic compounds and methods for preparation GENERAL ELECTRIC COMPANY (US) 2007-02-27 US disclosed