Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 17/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 13/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790371 | 1.00 | HCRTR1 (0.47) | HCRTR1HCRTR2CYP3A4DPP4 | |
| SCHEMBL13309233 | 0.86 | HCRTR1 (0.43) | HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL262575 | 0.85 | ITGB1 (0.45) | HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL6519881 | 0.84 | HCRTR1 (0.54) | HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL2796617 | 0.83 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL7910556 | 0.82 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL3385637 | 0.82 | CYP3A4 (0.50) | HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL3385643 | 0.82 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL3388555 | 0.80 | CYP3A4 (0.73) | HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL7912839 | 0.80 | CYP3A4 (0.73) | HCRTR1HCRTR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144760-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144760-A1 | NOVEL COMPOUNDS | HTR3B, HTR1B, HTR2B | HCRTR1 2016/4885HCRTR2 1425/4885CYP3A4 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.