Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 8/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 8/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 8/20 | 0.38 |
| ▸ | GBA1 | P04062 | 3/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392430 | 0.94 | KCNJ6 (0.39) | KCNJ6KCNJ5KCNJ3GBA1BRAF | |
| SCHEMBL3388802 | 0.93 | KCNJ6 (0.41) | KCNJ6KCNJ5KCNJ3GBA1DGAT1 | |
| SCHEMBL3392133 | 0.88 | KCNJ6 (0.34) | KCNJ6KCNJ5KCNJ3BRAFKMT2A | |
| SCHEMBL3393260 | 0.86 | KCNJ6 (0.40) | KCNJ6KCNJ5KCNJ3BRAFALDH1A1 | |
| SCHEMBL3390667 | 0.85 | KCNJ6 (0.45) | KCNJ6KCNJ5KCNJ3GBA1DGAT1 | |
| SCHEMBL3390681 | 0.85 | KCNJ6 (0.41) | KCNJ6KCNJ5KCNJ3GBA1NPY2R | |
| SCHEMBL3391094 | 0.84 | KCNJ6 (0.47) | KCNJ6KCNJ5KCNJ3GBA1DGAT1 | |
| SCHEMBL3392426 | 0.79 | KCNJ6 (0.50) | KCNJ6KCNJ5KCNJ3GBA1BRAF | |
| SCHEMBL3422863 | 0.78 | KCNJ6 (0.40) | KCNJ6KCNJ5KCNJ3KMT2AKDM4E | |
| SCHEMBL3388799 | 0.78 | KCNJ6 (0.49) | KCNJ6KCNJ5KCNJ3GBA1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943243-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2010-12-29 | — | — | EP | disclosed |