Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090139 | 0.93 | SLC6A2 (0.41) | PRCPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27466565 | 0.80 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL447293 | 0.76 | — | — | |
| SCHEMBL26491308 | 0.70 | SLC6A2 (0.48) | PRCPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20622101 | 0.70 | SLC6A2 (0.48) | PRCPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19242291 | 0.70 | SLC6A2 (0.48) | PRCPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6163254 | 0.70 | TSHR (0.41) | TSHR | |
| SCHEMBL1524591 | 0.70 | TSHR (0.41) | TSHR | |
| SCHEMBL1534018 | 0.70 | TSHR (0.41) | TSHR | |
| SCHEMBL6159886 | 0.70 | TSHR (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043633-A1 | 2H-PYRAZOLO [4,3-D]PYRIMIDIN-5-AMINE DERIVATIVES AS H4 HISTAMINE RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ALLERGIC, IMMUNOLOGICAL AND INFLAMMATORY DISEASES | PALAU PHARMA, S. A. (ES) | 2010-04-22 | — | — | WO | disclosed |